SCHEMBL22366363

SCHEMBL22366363

CC(=O)Oc1ccc(C#N)n1C

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PGR P06401 11/20 0.47
AR P10275 10/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4679923 0.73 AR (0.42) PGRAR
SCHEMBL61948 0.72 AR (0.41) PGRAR
SCHEMBL2002285 0.71 AR (0.54) PGRAR
SCHEMBL18921488 0.68 PGR (0.47) PGRAR
SCHEMBL31038643 0.67 PGR (0.46) PGRAR
SCHEMBL27860826 0.67 CA2 (0.39)
SCHEMBL91097 0.66 AR (0.46) PGRAR
SCHEMBL61947 0.66 AR (0.46) PGRAR
SCHEMBL27502842 0.66 PGR (0.36) PGRAR
SCHEMBL27523835 0.66 POLB (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3700911-A1 NOVEL MACROCYCLIC DERIVATIVES, PROCESS FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME Les Laboratoires Servier SAS (FR) 2020-09-02 EP disclosed