Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29401833 | 1.00 | ALDH1A1 (0.46) | ALDH1A1CYP1A2TDP1ABCB11NR3C1 | |
| SCHEMBL1901940 | 0.80 | CYP3A4 (0.50) | ALDH1A1CYP1A2TDP1CYP3A4HPGD | |
| SCHEMBL29668094 | 0.79 | ALDH1A1 (0.48) | ALDH1A1CYP1A2TDP1ABCB11NR3C1 | |
| SCHEMBL895789 | 0.79 | ALDH1A1 (0.48) | ALDH1A1CYP1A2TDP1ABCB11NR3C1 | |
| SCHEMBL29401009 | 0.79 | ALDH1A1 (0.52) | ALDH1A1CYP1A2TDP1ABCB11NR3C1 | |
| SCHEMBL458499 | 0.79 | ALDH1A1 (0.52) | ALDH1A1CYP1A2TDP1ABCB11NR3C1 | |
| SCHEMBL17289579 | 0.78 | ALDH1A1 (0.47) | ALDH1A1CYP1A2TDP1ABCB11NR3C1 | |
| SCHEMBL7808363 | 0.76 | ALDH1A1 (0.46) | ALDH1A1CYP1A2TDP1ABCB11NR3C1 | |
| SCHEMBL2768908 | 0.76 | ALDH1A1 (0.46) | ALDH1A1CYP1A2TDP1ABCB11NR3C1 | |
| SCHEMBL7256052 | 0.76 | ALDH1A1 (0.46) | ALDH1A1CYP1A2TDP1ABCB11NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3958865-B1 | 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES | BAYER AG (DE) | 2025-12-10 | — | — | EP | disclosed |
| US-12403135-B2 | 4H-pyrrolo[3,2-c]pyridin-4-one derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2025-09-02 | — | — | US | disclosed |
| EP-3700904-B1 | 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES | BAYER AG (DE) | 2023-07-19 | — | — | EP | disclosed |
| EP-3700904-B1 | 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES | BAYER AG (DE) | 2023-07-19 | — | — | EP | disclosed |
| US-20220378762-A1 | 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-01 | — | — | US | disclosed |
| US-11339157-B1 | 4H-pyrrolo[3,2-c]pyridin-4-one derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2022-05-24 | — | — | US | disclosed |
| US-11339157-B1 | 4H-pyrrolo[3,2-c]pyridin-4-one derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2022-05-24 | — | — | US | disclosed |
| EP-3958865-A1 | 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2022-03-02 | — | — | EP | disclosed |
| WO-2020216774-A1 | 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-10-29 | — | — | WO | disclosed |
| WO-2020216774-A1 | 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-10-29 | — | — | WO | disclosed |
| EP-3700904-A1 | 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES | Bayer AG (DE) | 2020-09-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220378762-A1 | 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES | EGFR, ERBB2, ERBB4 | ALDH1A1 1255/4885CYP1A2 577/4885TDP1 1060/4885 |
| US-12403135-B2 | 4H-pyrrolo[3,2-c]pyridin-4-one derivatives | EGFR, ERBB2, ERBB4 | ALDH1A1 1255/4885CYP1A2 577/4885TDP1 1060/4885 |
| US-11339157-B1 | 4H-pyrrolo[3,2-c]pyridin-4-one derivatives | CYP4B1, CYP2C19, CYP3A4 | ALDH1A1 387/4885CYP1A2 14/4885TDP1 2558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.