SCHEMBL29401009

SCHEMBL29401009

S=C=Nc1ccccc1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
TDP1 Q9NUW8 2/20 0.52
HPGD P15428 2/20 0.52
ABCB11 O95342 1/20 0.52
NR3C1 P04150 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
ADRA2A P08913 1/20 0.52
ADORA3 P0DMS8 1/20 0.52
ALOX15 P16050 1/20 0.52
ADRA2C P18825 1/20 0.52
MAOA P21397 1/20 0.52
DRD1 P21728 1/20 0.52
SLC6A4 P31645 1/20 0.52
HTR2B P41595 1/20 0.52
CCR2 P41597 1/20 0.52
HSD17B10 Q99714 1/20 0.52
HTR3E A5X5Y0 2/20 0.50
HTR3B O95264 2/20 0.50
HTR3A P46098 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL458499 1.00 ALDH1A1 (0.52) ALDH1A1TDP1HPGDABCB11NR3C1
Acetonitrile SCHEMBL27878183 0.90 ALDH1A1 (0.44) ALDH1A1TDP1HPGDABCB11NR3C1
SCHEMBL8592479 0.88 ALDH1A1 (0.43) ALDH1A1TDP1HPGDABCB11NR3C1
SCHEMBL15989929 0.83 ALDH1A1 (0.46) ALDH1A1TDP1HPGDABCB11NR3C1
SCHEMBL895789 0.82 ALDH1A1 (0.48) ALDH1A1TDP1HPGDABCB11NR3C1
SCHEMBL29668094 0.82 ALDH1A1 (0.48) ALDH1A1TDP1HPGDABCB11NR3C1
SCHEMBL207554 0.82 ALDH1A1 (0.62) ALDH1A1TDP1HPGDABCB11NR3C1
SCHEMBL29374052 0.82 ALDH1A1 (0.62) ALDH1A1TDP1HPGDABCB11NR3C1
SCHEMBL17289579 0.80 ALDH1A1 (0.47) ALDH1A1TDP1HPGDABCB11NR3C1
SCHEMBL444165 0.80 HTR3E (0.54) ALDH1A1TDP1HPGDCYP1A2HTR3E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119080660-A Thiosemicarbazide menthyl formate compound, preparation method and application thereof 南京林业大学 2024-12-06 CN claimed
CN-114516848-B Preparation method of polycarbonate high-temperature degradation resistant agent and polycarbonate composition 万华化学集团股份有限公司 2024-02-02 CN claimed
EP-4280882-A2 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. (US) 2023-11-29 EP claimed
WO-2022159439-A2 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. (US) 2022-07-28 WO claimed
CN-119080660-A Thiosemicarbazide menthyl formate compound, preparation method and application thereof 南京林业大学 2024-12-06 CN disclosed
CN-114516848-B Preparation method of polycarbonate high-temperature degradation resistant agent and polycarbonate composition 万华化学集团股份有限公司 2024-02-02 CN disclosed
CN-114516848-A Preparation method of polycarbonate high-temperature degradation resistant agent and polycarbonate composition 万华化学集团股份有限公司 2022-05-20 CN disclosed
EP-3958865-A1 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES Bayer Aktiengesellschaft (DE) 2022-03-02 EP disclosed