Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 6/20 | 0.33 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21802977 | 1.00 | HCAR2 (0.42) | HCAR2ATMTSHRALDH1A1CYP3A4 | |
| SCHEMBL22367597 | 1.00 | HCAR2 (0.42) | HCAR2ATMTSHRALDH1A1CYP3A4 | |
| SCHEMBL21802955 | 1.00 | HCAR2 (0.42) | HCAR2ATMTSHRALDH1A1CYP3A4 | |
| SCHEMBL22367592 | 1.00 | HCAR2 (0.42) | HCAR2ATMTSHRALDH1A1CYP3A4 | |
| SCHEMBL21802985 | 0.98 | ATM (0.43) | HCAR2ATMTSHRALDH1A1CYP3A4 | |
| SCHEMBL49180 | 0.93 | ATM (0.44) | HCAR2ATMTSHRALDH1A1CYP3A4 | |
| SCHEMBL22367605 | 0.87 | HCAR2 (0.42) | HCAR2ATMTSHRALDH1A1CYP3A4 | |
| SCHEMBL22367594 | 0.87 | HCAR2 (0.42) | HCAR2ATMTSHRALDH1A1CYP3A4 | |
| SCHEMBL22367601 | 0.87 | HCAR2 (0.42) | HCAR2ATMTSHRALDH1A1CYP3A4 | |
| SCHEMBL22367584 | 0.87 | HCAR2 (0.42) | HCAR2ATMTSHRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023136337-A1 | DENTAL COMPOSITION, METHOD FOR MANUFACTURING SAME, AND DENTAL SURFACE-TREATED FILLER | クラレノリタケデンタル株式会社 | 2023-07-20 | — | — | WO | disclosed |
| WO-2023106419-A1 | DENTAL CURABLE COMPOSITION | クラレノリタケデンタル株式会社 | 2023-06-15 | — | — | WO | disclosed |
| US-11607370-B2 | Dental composition | KURARAY NORITAKE DENTAL INC. (JP) | 2023-03-21 | — | — | US | disclosed |
| US-20210186823-A1 | DENTAL COMPOSITION | KURARAY NORITAKE DENTAL INC. (JP) | 2021-06-24 | — | — | US | disclosed |
| EP-3701930-A1 | DENTAL COMPOSITION | Kuraray Noritake Dental Inc. (JP) | 2020-09-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11607370-B2 | Dental composition | ITGAL, ITGA1, ITGB3 | HCAR2 3100/4885ATM 2877/4885TSHR 4827/4885 |
| US-20210186823-A1 | DENTAL COMPOSITION | ITGAL, ITGA1, ITGB3 | HCAR2 3100/4885ATM 2877/4885TSHR 4827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.