Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.53 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 8/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28778155 | 0.79 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2GAAALDH1A1TSHR | |
| SCHEMBL4344395 | 0.78 | ZDHHC20 (0.61) | ZDHHC20ZDHHC2GAAALDH1A1TSHR | |
| SCHEMBL24119207 | 0.76 | ZDHHC20 (0.65) | ZDHHC20ZDHHC2GAAALDH1A1TSHR | |
| SCHEMBL4653768 | 0.76 | ZDHHC20 (0.55) | ZDHHC20ZDHHC2GAAALDH1A1TSHR | |
| SCHEMBL24932940 | 0.76 | ZDHHC20 (0.46) | ZDHHC20ZDHHC2GAAALDH1A1TSHR | |
| Ammonia Solution, Strong SCHEMBL29386805 | 0.76 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2GAAALDH1A1TSHR | |
| SCHEMBL9067240 | 0.76 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2GAAALDH1A1TSHR | |
| SCHEMBL20925263 | 0.76 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2GAAALDH1A1TSHR | |
| SCHEMBL632264 | 0.76 | ZDHHC20 (0.75) | ZDHHC20ZDHHC2GAAALDH1A1TSHR | |
| SCHEMBL1561467 | 0.76 | ZDHHC20 (0.68) | ZDHHC20ZDHHC2GAAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3494168-B9 | POLYMER COMPOSITIONS CONTAINING GRAFTED POLYMERIC NETWORKS AND PROCESSES FOR THEIR PREPARATION AND USE | JOHNSON & JOHNSON VISION CARE (US) | 2020-08-26 | — | — | EP | disclosed |