SCHEMBL632264

SCHEMBL632264

C=CC(=O)NCCCCNC(=O)C=C

nearest known ligand 0.75

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.75
ZDHHC2 Q9UIJ5 1/20 0.75
ALDH1A1 P00352 3/20 0.62
MAPK1 P28482 2/20 0.62
TSHR P16473 2/20 0.62
TDP1 Q9NUW8 1/20 0.62
MAPT P10636 1/20 0.52
TGM2 P21980 7/20 0.50
GAA P10253 1/20 0.46
KDM4E B2RXH2 1/20 0.42
HIF1A Q16665 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
POLB P06746 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL58169 0.97 ZDHHC20 (0.79) ZDHHC20ZDHHC2ALDH1A1MAPK1TSHR
SCHEMBL1592093 0.97 ZDHHC20 (0.79) ZDHHC20ZDHHC2ALDH1A1MAPK1TSHR
SCHEMBL1401845 0.97 ZDHHC20 (0.79) ZDHHC20ZDHHC2ALDH1A1MAPK1TSHR
SCHEMBL1591868 0.97 ZDHHC20 (0.79) ZDHHC20ZDHHC2ALDH1A1MAPK1TSHR
SCHEMBL270209 0.97 ZDHHC20 (0.79) ZDHHC20ZDHHC2ALDH1A1MAPK1TSHR
SCHEMBL269468 0.97 ZDHHC20 (0.79) ZDHHC20ZDHHC2ALDH1A1MAPK1TSHR
SCHEMBL8405507 0.97 ZDHHC20 (0.79) ZDHHC20ZDHHC2ALDH1A1MAPK1TSHR
SCHEMBL1561467 0.94 ZDHHC20 (0.68) ZDHHC20ZDHHC2ALDH1A1MAPK1TSHR
SCHEMBL8040424 0.91 ZDHHC20 (0.64) ZDHHC20ZDHHC2ALDH1A1MAPK1TSHR
SCHEMBL155436 0.91 ZDHHC20 (0.64) ZDHHC20ZDHHC2ALDH1A1MAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 553 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250017827-A1 Acid-Stable Glass Fillers And Self-Adhesive Dental Composite Cements With Good Transparency Containing Them IVOCLAR VIVADENT AG (LI) 2025-01-16 US claimed
EP-4488243-A1 ACID-STABLE GLASS FILLERS AND SELF-ADHESIVE DENTAL COMPOSITE CEMENTS CONTAINING SAME HAVING GOOD TRANSPARENCY Ivoclar Vivadent AG (LI) 2025-01-08 EP claimed
US-20240158614-A1 STORAGE STABLE SELF-ADHESIVE COMPOSITE CEMENTS WITH GOOD TRANSPARENCY AND GOOD RADIOPACITY IVOCLAR VIVADENT AG (LI) 2024-05-16 US claimed
EP-4356893-A1 STORAGE STABLE SELF-ADHESIVE COMPOSITE CEMENTS WITH GOOD TRANSPARENCY AND GOOD RADIOPACITY Ivoclar Vivadent AG (LI) 2024-04-24 EP claimed
CN-117917236-A Storage-stable self-adhesive composite cements with good transparency and good radiopacity 义获嘉伟瓦登特公司 2024-04-23 CN claimed
US-20230382066-A1 SILICONE HYDROGEL COMPOSITION AND SILICONE HYDROGEL LENS PEGAVISION CORPORATION (TW) 2023-11-30 US claimed
US-11760045-B2 Silicone hydrogel composition, silicone hydrogel lens, and method of manufacturing silicone hydrogel lens PEGAVISION CORPORATION (TW) 2023-09-19 US claimed
EP-4205724-A1 SELF-ADHESIVE DENTAL COMPOSITE CEMENTS WITH GOOD TRANSPARENCY BASED ON ACID-TREATED FILLERS Ivoclar Vivadent AG (LI) 2023-07-05 EP claimed
EP-4205722-A1 SELF-ADHESIVE DENTAL COMPOSITE WITH GOOD TRANSPARENCY Ivoclar Vivadent AG (LI) 2023-07-05 EP claimed
EP-4205723-A1 HIGH TRANSPARENCY, SULPHATE-CONTAINING OR PHOSPHATE-CONTAINING DENTAL SELF-ADHERING COMPOSITE Ivoclar Vivadent AG (LI) 2023-07-05 EP claimed
EP-1413569-A1 Bicyclic cyclopropane derivatives capable of polymerisation and their use in the preparation of dental materials Ivoclar Vivadent AG (LI) 2004-04-28 EP claimed
US-20040077882-A1 Polymerizable bicyclic cyclopropane derivatives and their use for the preparation of dental materials IVOCLAR VIVADENT AG (LI) 2004-04-22 US claimed
US-20040077754-A1 Dental materials based on acrylic-ester phosphonic acids IVOCLAR VIVADENT AG (LI) 2004-04-22 US claimed
EP-1374829-A1 Dental material on the basis of acryloester phosphonic acid Ivoclar Vivadent AG (LI) 2004-01-02 EP claimed
EP-0606742-B1 Bile acid sequestrant ROHM & HAAS (US) 1997-11-19 EP claimed
US-5451397-A Crosslinked amino functional acrylic amide polymer, reducing blood cholesterol levels ROHM AND HAAS COMPANY (US) 1995-09-19 US claimed
EP-0606742-A1 Bile acid sequestrant ROHM AND HAAS COMPANY (US) 1994-07-20 EP claimed
US-5084509-A Peptides or proteins bound to aminoalkyl polydimethylacrylamide for immunology BAYLOR COLLEGE OF MEDICINE (US) 1992-01-28 US claimed
US-4973638-A DIMETHYLACRYLAMIDE, N-ACRYLYL DIAMINOALKANE, CROSSLINKER, AND EMULSIFIER SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCHE (US) 1990-11-27 US claimed
US-4626581-A CROSSLINKED ACRYLAMIDE INTERPOLYMERS BOARD OF REGENTS, UNIVERSITY OF TEXAS (US) 1986-12-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040077882-A1 Polymerizable bicyclic cyclopropane derivatives and their use for the preparation of dental materials SCO2, CBR1, CORO1C ZDHHC20 515/4885ZDHHC2 734/4885ALDH1A1 1884/4885
US-20040077754-A1 Dental materials based on acrylic-ester phosphonic acids PHOSPHO1, RER1, PTGER1 ZDHHC20 3918/4885ZDHHC2 3679/4885ALDH1A1 804/4885
US-20250017827-A1 Acid-Stable Glass Fillers And Self-Adhesive Dental Composite Cements With Good Transparency Containing Them HAO2, HAO1, CDH1 ZDHHC20 3093/4885ZDHHC2 3420/4885ALDH1A1 1494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.