SCHEMBL2236766

SCHEMBL2236766

Nc1ccccc1C(=O)NCc1ccccc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 8/20 0.77
KDM4E B2RXH2 5/20 0.77
ALDH1A1 P00352 5/20 0.77
NSD2 O96028 2/20 0.77
HSD17B10 Q99714 1/20 0.70
KMT2A Q03164 4/20 0.69
USP2 O75604 1/20 0.65
GAA P10253 2/20 0.65
LMNA P02545 1/20 0.65
L3MBTL1 Q9Y468 1/20 0.65
APEX1 P27695 1/20 0.64
METAP2 P50579 1/20 0.63
CHRNB2 P17787 1/20 0.63
CHRNB4 P30926 1/20 0.63
CHRNA3 P32297 1/20 0.63
CHRNA4 P43681 1/20 0.63
TP53 P04637 1/20 0.59
GLA P06280 1/20 0.59
SGMS2 Q8NHU3 1/20 0.58
RCE1 Q9Y256 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycine SCHEMBL29048907 0.94 HPGD (0.68) HPGDKDM4EALDH1A1NSD2HSD17B10
SCHEMBL1060622 0.89 HPGD (0.71) HPGDKDM4EALDH1A1NSD2HSD17B10
SCHEMBL6038030 0.87 HPGD (0.73) HPGDKDM4EALDH1A1NSD2HSD17B10
SCHEMBL28728994 0.87 HPGD (0.73) HPGDKDM4EALDH1A1NSD2HSD17B10
SCHEMBL4478849 0.87 NSD2 (1.00) HPGDKDM4EALDH1A1NSD2HSD17B10
SCHEMBL14727423 0.87 ALDH1A1 (0.73) HPGDKDM4EALDH1A1NSD2HSD17B10
SCHEMBL28901311 0.87 ALDH1A1 (0.73) HPGDKDM4EALDH1A1NSD2HSD17B10
SCHEMBL28730014 0.87 HPGD (1.00) HPGDKDM4EALDH1A1NSD2HSD17B10
SCHEMBL29433995 0.87 HPGD (1.00) HPGDKDM4EALDH1A1NSD2HSD17B10
SCHEMBL31680569 0.87 KMT2A (0.89) HPGDNSD2KMT2AUSP2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119661459-A 1,2, 3-Benzotriazine-4 (3H) -one seleno compound and preparation method and application thereof 赣南师范大学 2025-03-21 CN claimed
CN-118184588-A N-aryl/alkyl quinazolinone compound and synthesis method thereof 陕西科技大学 2024-06-14 CN claimed
EP-4608817-A1 COMPOUNDS AND METHODS FOR TREATING CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-09-03 EP disclosed
CN-119661459-A 1,2, 3-Benzotriazine-4 (3H) -one seleno compound and preparation method and application thereof 赣南师范大学 2025-03-21 CN disclosed
CN-118184588-A N-aryl/alkyl quinazolinone compound and synthesis method thereof 陕西科技大学 2024-06-14 CN disclosed
WO-2024091450-A1 COMPOUNDS AND METHODS FOR TREATING CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-05-02 WO disclosed
WO-2024091450-A1 COMPOUNDS AND METHODS FOR TREATING CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-05-02 WO disclosed
CN-114276203-B Method for synthesizing 2-aminobenzamide compound by ultraviolet light induction 湖南大学 2023-03-31 CN disclosed
CN-111646908-B Method for preparing aromatic amine compound 宜昌尚诺德生物医药科技有限公司 2023-03-10 CN disclosed
CN-111732493-B Synthesis process of arylamine compound 宜昌尚诺德生物医药科技有限公司 2023-01-24 CN disclosed
CN-114276203-A Method for synthesizing 2-aminobenzamide compound by ultraviolet light induction 湖南大学 2022-04-05 CN disclosed
CN-1017242-B NEW QUIANZOLINE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION FUJISAWA PHARMACEUTICAL CO (JP) 1992-07-01 CN disclosed
US-4883800-A DIABETES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-11-28 US disclosed
EP-0145225-B1 RECORD MATERIAL The Wiggins Teape Group Limited (GB) 1989-10-04 EP disclosed
US-4734419-A Quinazoline derivatives, compositions thereof and their use in treating diabetic complications FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-03-29 US disclosed
CN-86106984-A New quinazoline derivant and preparation method thereof 1987-05-20 CN disclosed
EP-0218999-A2 New quinazoline derivatives, process for their production and pharmaceutical compositions comprising them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1987-04-22 EP disclosed
US-4642322-A Stabilization of chlorine-containing thermoplastics with nitrogen-containing organic compounds CIBA-GEIGY CORPORATION (US) 1987-02-10 US disclosed
US-4587538-A Record material THE WIGGINS TEAPE GROUP LIMITED (GB) 1986-05-06 US disclosed
EP-0145225-A2 Record material The Wiggins Teape Group Limited (GB) 1985-06-19 EP disclosed