Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | DAO | P14920 | 1/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL20543364 | 0.92 | TSHR (0.52) | TSHRDAONAPRTTRPA1CES1 | |
| Isophthalic Acid SCHEMBL10818061 | 0.89 | CA12 (0.47) | TRPA1MAPTSMN1; SMN2KMT2AHPGD | |
| Isophthalic Acid SCHEMBL20543217 | 0.89 | CA12 (0.47) | TRPA1MAPTSMN1; SMN2KMT2AHPGD | |
| Benzoic Acid SCHEMBL28596822 | 0.88 | TSHR (0.56) | TSHRDAONAPRTTRPA1CES1 | |
| Benzoic Acid SCHEMBL27547235 | 0.88 | TSHR (0.56) | TSHRDAONAPRTTRPA1CES1 | |
| Benzoic Acid SCHEMBL27567445 | 0.88 | TRPA1 (0.53) | TSHRDAONAPRTTRPA1CES1 | |
| Benzoic Acid SCHEMBL227466 | 0.86 | TSHR (0.54) | TSHRDAONAPRTTRPA1CES1 | |
| Benzoic Acid SCHEMBL11707346 | 0.86 | TSHR (0.54) | TSHRDAONAPRTTRPA1CES1 | |
| Benzoic Acid SCHEMBL574292 | 0.86 | DAO (0.45) | TSHRDAONAPRTTRPA1CES1 | |
| Benzoic Acid SCHEMBL27590662 | 0.85 | TSHR (0.52) | TSHRDAONAPRTTRPA1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230376-A1 | POLY(VINYL ACETAL) RESIN COMPOSITIONS, LAYERS, AND INTERLAYERS HAVING ENHANCED OPTICAL PROPERTIES | Solutia Inc. (US) | 2017-10-18 | — | — | EP | claimed |
| US-9587086-B2 | Poly(vinyl acetal) resin compositions, layers, and interlayers having enhanced optical properties | EASTMAN CHEMICAL COMPANY (US) | 2017-03-07 | — | — | US | claimed |
| WO-2016094203-A1 | POLY(VINYL ACETAL) RESIN COMPOSITIONS, LAYERS, AND INTERLAYERS HAVING ENHANCED OPTICAL PROPERTIES | SOLUTIA INC. (US) | 2016-06-16 | — | — | WO | claimed |
| US-20160160005-A1 | POLY(VINYL ACETAL) RESIN COMPOSITIONS, LAYERS, AND INTERLAYERS HAVING ENHANCED OPTICAL PROPERTIES | SOLUTION INC. (US) | 2016-06-09 | — | — | US | claimed |
| EP-3230376-B1 | POLY(VINYL ACETAL) RESIN COMPOSITIONS, LAYERS, AND INTERLAYERS HAVING ENHANCED OPTICAL PROPERTIES | SOLUTIA INC (US) | 2025-09-24 | — | — | EP | disclosed |
| US-11358376-B2 | Poly(vinyl acetal) resin compositions, layers, and interlayers having enhanced optical properties | SOLUTIA INC. (US) | 2022-06-14 | — | — | US | disclosed |
| CN-107207817-B | Poly (vinyl acetal) resin compositions, layers and interlayers having enhanced optical properties | 首诺公司 | 2021-01-05 | — | — | CN | disclosed |
| US-10563057-B2 | Poly(vinyl acetal) resin compositions, layers, and interlayers having enhanced optical properties | SOLUTIA INC. (US) | 2020-02-18 | — | — | US | disclosed |
| EP-2647668-B1 | POLYESTER RESIN COMPOSITION AND MOLDED BODY OF SAME | ADEKA CORP (JP) | 2019-08-14 | — | — | EP | disclosed |
| US-20190202179-A1 | POLY(VINYL ACETAL) RESIN COMPOSITIONS, LAYERS, AND INTERLAYERS HAVING ENHANCED OPTICAL PROPERTIES | SOLUTIA INC. (US) | 2019-07-04 | — | — | US | disclosed |
| EP-3075784-B1 | PROCESS FOR PRODUCING MASTERBATCH | ADEKA CORP (JP) | 2018-10-03 | — | — | EP | disclosed |
| US-9963583-B2 | Poly(vinyl acetal) resin compositions, layers, and interlayers having enhanced optical properties | SOLUTIA INC. (US) | 2018-05-08 | — | — | US | disclosed |
| US-20160159051-A1 | POLY(VINYL ACETAL) RESIN COMPOSITIONS, LAYERS, AND INTERLAYERS HAVING ENHANCED OPTICAL PROPERTIES | SOLUTIA INC. (US) | 2016-06-09 | — | — | US | disclosed |
| US-20140350139-A1 | METHOD FOR PRODUCING MASTERBATCHES | ADEKA CORPORATION (JP) | 2014-11-27 | — | — | US | disclosed |
| EP-2796487-A1 | METHOD FOR PRODUCING MASTERBATCHES | Adeka Corporation (JP) | 2014-10-29 | — | — | EP | disclosed |
| US-8829084-B2 | Reinforced polyester resin composition | ADEKA CORPORATION (JP) | 2014-09-09 | — | — | US | disclosed |
| EP-2647668-A1 | POLYESTER RESIN COMPOSITION AND MOLDED BODY OF SAME | Adeka Corporation (JP) | 2013-10-09 | — | — | EP | disclosed |
| US-20130253145-A1 | POLYESTER RESIN COMPOSITION AND MOLDED BODY OF SAME | ADEKA CORPORATION (JP) | 2013-09-26 | — | — | US | disclosed |
| EP-2407514-A1 | REINFORCED POLYESTER RESIN COMPOSITION | Adeka Corporation (JP) | 2012-01-18 | — | — | EP | disclosed |
| US-20120004363-A1 | REINFORCED POLYESTER RESIN COMPOSITION | ADEKA CORPORATION (JP) | 2012-01-05 | — | — | US | disclosed |