Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 15/20 | 0.39 |
| ▸ | FLT3 | P36888 | 3/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.36 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.36 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15821395 | 0.76 | FLT3 (0.47) | ALKFLT3SRPK2SRPK1EML4 | |
| SCHEMBL29818492 | 0.76 | FLT3 (0.47) | ALKFLT3SRPK2SRPK1EML4 | |
| SCHEMBL22369276 | 0.75 | ALK (0.55) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL30009067 | 0.71 | ALK (0.46) | ALKFLT3 | |
| SCHEMBL6008260 | 0.70 | KIF11 (0.58) | ALKITK | |
| SCHEMBL20356899 | 0.69 | MAPK10 (0.46) | ITK | |
| SCHEMBL31737740 | 0.69 | MAPK10 (0.46) | ITK | |
| SCHEMBL12727213 | 0.69 | ALDH1A1 (0.45) | METAP1 | |
| SCHEMBL31507375 | 0.67 | ALK (0.70) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL20366576 | 0.67 | ALK (0.70) | ALKSRPK2SRPK1EML4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3698788-A1 | COMPOSITION COMPRISING TETRACYCLIC COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2020-08-26 | — | — | EP | disclosed |