Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.76 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22370234 | 1.00 | ALDH1A1 (0.76) | ALDH1A1TDP1GPBAR1MAPK1GABRA1 | |
| SCHEMBL16903901 | 0.88 | GPBAR1 (0.60) | ALDH1A1TDP1GPBAR1MAPK1GABRA1 | |
| SCHEMBL1081229 | 0.86 | ALDH1A1 (1.00) | ALDH1A1TDP1GPBAR1MAPK1GABRA1 | |
| SCHEMBL11726722 | 0.86 | ALDH1A1 (1.00) | ALDH1A1TDP1GPBAR1MAPK1GABRA1 | |
| SCHEMBL1081228 | 0.86 | ALDH1A1 (1.00) | ALDH1A1TDP1GPBAR1MAPK1GABRA1 | |
| SCHEMBL4865817 | 0.85 | ALDH1A1 (0.76) | ALDH1A1TDP1GPBAR1MAPK1GABRA1 | |
| SCHEMBL16950285 | 0.85 | ALDH1A1 (0.76) | ALDH1A1TDP1GPBAR1MAPK1GABRA1 | |
| Hydrochloric Acid SCHEMBL1081962 | 0.85 | ALDH1A1 (0.97) | ALDH1A1TDP1GPBAR1MAPK1GABRA1 | |
| SCHEMBL11730438 | 0.85 | ALDH1A1 (0.97) | ALDH1A1TDP1GPBAR1MAPK1GABRA1 | |
| SCHEMBL16903909 | 0.83 | GPBAR1 (0.56) | ALDH1A1TDP1GPBAR1MAPK1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200277264-A1 | Compounds for Treating Disorders Associated with Abnormal Steroidogenesis | THE GENERAL HOSPITAL CORPORATION | 2020-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200277264-A1 | Compounds for Treating Disorders Associated with Abnormal Steroidogenesis | CYP27A1, HSD17B11, NR5A1 | ALDH1A1 459/4885TDP1 3134/4885GPBAR1 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.