Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22371423 | 0.93 | ELANE (0.45) | ELANEMAPTTP53POLBTDP1 | |
| SCHEMBL31135851 | 0.93 | ELANE (0.45) | ELANEMAPTTP53POLBTDP1 | |
| SCHEMBL25997472 | 0.79 | HPSE (0.49) | MAPTTP53POLBTDP1MIF | |
| SCHEMBL22371413 | 0.76 | MAPT (0.57) | MAPTTP53POLBTDP1MEN1 | |
| SCHEMBL22371415 | 0.76 | HSPD1 (0.40) | MAPTTP53POLBTDP1MIF | |
| SCHEMBL31135859 | 0.76 | HSPD1 (0.40) | MAPTTP53POLBTDP1MIF | |
| SCHEMBL22371405 | 0.75 | MAPT (0.53) | MAPTTP53POLBTDP1MEN1 | |
| SCHEMBL24239995 | 0.74 | MIF (0.43) | MAPTTP53POLBTDP1MEN1 | |
| SCHEMBL26972163 | 0.73 | KDM4E (0.55) | MAPTTP53MEN1KMT2AKDM4E | |
| SCHEMBL22371421 | 0.72 | AGPAT2 (0.46) | MAPTTP53POLBTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250002994-A1 | TERTIARY AMINE SUBSTITUTED COUMARIN COMPOUNDS AND USES AS FLUORESCENT LABELS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2025-01-02 | — | — | US | disclosed |
| US-12110546-B2 | Tertiary amine substituted coumarin compounds and uses as fluorescent labels | ILLUMINA CAMBRIDGE LIMITED (GB) | 2024-10-08 | — | — | US | disclosed |
| US-12031178-B2 | Cyclooctatetraene containing dyes and compositions | ILLUMINA CAMBRIDGE LIMITED (GB) | 2024-07-09 | — | — | US | disclosed |
| US-20230265502-A1 | CYCLOOCTATETRAENE CONTAINING DYES AND COMPOSITIONS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2023-08-24 | — | — | US | disclosed |
| US-20220049292-A1 | MULTIPLEXED FLUORESCENT DETECTION OF ANALYTES | ILLUMINA CAMBRIDGE LIMITED (GB) | 2022-02-17 | — | — | US | disclosed |
| US-20220049292-A1 | MULTIPLEXED FLUORESCENT DETECTION OF ANALYTES | ILLUMINA CAMBRIDGE LIMITED (GB) | 2022-02-17 | — | — | US | disclosed |
| US-20200277670-A1 | TERTIARY AMINE SUBSTITUTED COUMARIN COMPOUNDS AND USES AS FLUORESCENT LABELS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2020-09-03 | — | — | US | disclosed |
| US-20200277670-A1 | TERTIARY AMINE SUBSTITUTED COUMARIN COMPOUNDS AND USES AS FLUORESCENT LABELS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2020-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12110546-B2 | Tertiary amine substituted coumarin compounds and uses as fluorescent labels | FBL, NAT10, DNMT3A | ELANE 3468/4885MAPT 1401/4885TP53 478/4885 |
| US-20200277670-A1 | TERTIARY AMINE SUBSTITUTED COUMARIN COMPOUNDS AND USES AS FLUORESCENT LABELS | FBL, NAT10, DNMT3A | ELANE 3468/4885MAPT 1401/4885TP53 478/4885 |
| US-20250002994-A1 | TERTIARY AMINE SUBSTITUTED COUMARIN COMPOUNDS AND USES AS FLUORESCENT LABELS | FBL, NAT10, DNMT3A | ELANE 3468/4885MAPT 1401/4885TP53 478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.