Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 14/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22371415 | 0.87 | HSPD1 (0.40) | HPSETP53MAPTSMN1; SMN2NPC1 | |
| SCHEMBL31135859 | 0.87 | HSPD1 (0.40) | HPSETP53MAPTSMN1; SMN2NPC1 | |
| SCHEMBL31135851 | 0.86 | ELANE (0.45) | HPSETP53MAPTRAB9APOLB | |
| SCHEMBL22371423 | 0.86 | ELANE (0.45) | HPSETP53MAPTRAB9APOLB | |
| SCHEMBL26073482 | 0.85 | AGPAT2 (0.49) | TP53MAPTSMN1; SMN2NPC1HPGD | |
| SCHEMBL26869917 | 0.83 | KDM4E (0.50) | HPSETP53MAPTSMN1; SMN2NPC1 | |
| SCHEMBL29761153 | 0.83 | ALDH1A1 (0.60) | TP53MAPTSMN1; SMN2NPC1HPGD | |
| SCHEMBL17445577 | 0.83 | ALDH1A1 (0.60) | TP53MAPTSMN1; SMN2NPC1HPGD | |
| SCHEMBL22371457 | 0.82 | MAPT (0.53) | HPSETP53MAPTSMN1; SMN2NPC1 | |
| SCHEMBL25997471 | 0.80 | ITGB3 (0.37) | HPSETP53MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12031178-B2 | Cyclooctatetraene containing dyes and compositions | ILLUMINA CAMBRIDGE LIMITED (GB) | 2024-07-09 | — | — | US | disclosed |
| US-20230265503-A1 | CYCLOOCTATETRAENE CONTAINING DYES AND COMPOSITIONS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2023-08-24 | — | — | US | disclosed |
| US-20230265502-A1 | CYCLOOCTATETRAENE CONTAINING DYES AND COMPOSITIONS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2023-08-24 | — | — | US | disclosed |