SCHEMBL22373752

SCHEMBL22373752

CCCCNC1(C)CC1(C)N

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA12 O43570 1/20 0.34
CA7 P43166 1/20 0.34
CA14 Q9ULX7 1/20 0.34
TSHR P16473 1/20 0.33
ALOX15 P16050 1/20 0.31
ADH1B P00325 1/20 0.30
ADH1C P00326 1/20 0.30
ADH1A P07327 1/20 0.30
ADH7 P40394 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21128288 0.71
SCHEMBL28632316 0.68 TSHR (0.30) TSHR
SCHEMBL30142446 0.64 TSHR (0.33) CA1CA2CA12CA7CA14
SCHEMBL9801530 0.64 TSHR (0.33) CA1CA2CA12CA7CA14
SCHEMBL9801614 0.62 TSHR (0.32) TSHRALOX15
SCHEMBL28770037 0.62 TSHR (0.32) TSHR
SCHEMBL9801202 0.62 TSHR (0.32) TSHRALOX15
SCHEMBL4565549 0.62 ALDH1A1 (0.39) TSHRADH1BADH1CADH1AADH7
Butane SCHEMBL7193953 0.61 ALOX15 (0.67) CA1CA2CA12CA7CA14
Butane SCHEMBL3876638 0.59 TSHR (0.73) CA1CA2CA12CA7CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11773320-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-03 US disclosed
US-11228004-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-01-18 US disclosed
US-20200274076-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2020-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11773320-B2 Organic electroluminescent materials and devices CCNL2, HCN4, HNRNPL CA1 3788/4885CA2 3337/4885CA12 3967/4885
US-11228004-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, ICOSLG CA1 3342/4885CA2 3392/4885CA12 2544/4885
US-20200274076-A1 Organic Electroluminescent Materials and Devices CCNL2, HCN4, HNRNPL CA1 3725/4885CA2 3275/4885CA12 3810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.