SCHEMBL22374237

SCHEMBL22374237

O=C(CI)Oc1cc(OC(=O)CI)cc(C(=O)O)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
PLA2G2A P14555 1/20 0.43
TPMT P51580 3/20 0.39
CA12 O43570 3/20 0.37
CA1 P00915 3/20 0.37
CA2 P00918 3/20 0.37
CA7 P43166 3/20 0.37
CA9 Q16790 3/20 0.37
CA14 Q9ULX7 3/20 0.37
AKR1C3 P42330 1/20 0.36
CA3 P07451 2/20 0.35
CA4 P22748 2/20 0.35
CA6 P23280 2/20 0.35
CA5A P35218 2/20 0.35
CA5B Q9Y2D0 2/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6693659 0.82 AKR1C3 (0.56) KMT2AAKR1C3NR4A2POLB
SCHEMBL6691150 0.80 HSD17B10 (0.52) KMT2ATPMTCA1CA2TP53
SCHEMBL19459341 0.80 KMT2A (0.52) KMT2AMEN1PLA2G2ATPMTCA12
SCHEMBL22279609 0.77 CA12 (0.33) KMT2AMEN1CA12CA1CA2
SCHEMBL1762271 0.72 CYP19A1 (0.52) KMT2AMEN1KDM4EALDH1A1LMNA
SCHEMBL20676026 0.72 MEN1 (0.56) KMT2AMEN1PLA2G2ATPMTCA12
SCHEMBL417129 0.72 HSD17B10 (0.57) KMT2AMEN1PLA2G2ATPMTKDM4E
SCHEMBL5025919 0.72 TPMT (0.44) KMT2AMEN1PLA2G2ATPMTCA12
SCHEMBL3681151 0.72 HSD17B10 (0.44) KMT2AMEN1PLA2G2AKDM4EALDH1A1
SCHEMBL27809607 0.71 CYP19A1 (0.50) KMT2AMEN1KDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11720020-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-08 US disclosed
US-11720020-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-08 US disclosed
US-11586110-B2 Positive resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-02-21 US disclosed
US-11415887-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-08-16 US disclosed
US-20210033971-A1 POSITIVE RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-02-04 US disclosed
US-20210033969-A1 CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-02-04 US disclosed
US-20210033970-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-02-04 US disclosed
US-20200272048-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-08-27 US disclosed