SCHEMBL1762271

SCHEMBL1762271

O=C(CI)Oc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.52
ELANE P08246 1/20 0.47
ATM Q13315 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
ALOX15 P16050 2/20 0.45
PRSS1 P07477 1/20 0.45
PRSS2 P07478 1/20 0.45
PRSS3 P35030 1/20 0.45
HSD17B10 Q99714 2/20 0.44
HPGD P15428 2/20 0.44
MAPT P10636 3/20 0.44
ALDH1A1 P00352 3/20 0.44
KMT2A Q03164 3/20 0.42
LMNA P02545 1/20 0.42
HTT P42858 1/20 0.42
KDM4E B2RXH2 1/20 0.41
NSD2 O96028 1/20 0.41
EGFR P00533 1/20 0.41
ERBB2 P04626 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27809607 0.98 CYP19A1 (0.50) CYP19A1ELANEATML3MBTL1TDP1
Acetic Acid SCHEMBL2217916 0.94 ELANE (0.47) CYP19A1ELANEATML3MBTL1TDP1
SCHEMBL6727690 0.84 CYP19A1 (0.53) CYP19A1ELANEATML3MBTL1TDP1
SCHEMBL153387 0.81 CYP19A1 (0.55) CYP19A1ELANEATML3MBTL1TDP1
SCHEMBL43742 0.81 KMT2A (0.61) CYP19A1ELANEATML3MBTL1TDP1
SCHEMBL6691150 0.81 HSD17B10 (0.52) ELANEHSD17B10KMT2AHTT
SCHEMBL15064174 0.80 PRSS1 (0.51) CYP19A1ELANEATML3MBTL1TDP1
SCHEMBL6693659 0.79 AKR1C3 (0.56) KMT2A
SCHEMBL593272 0.79 CYP19A1 (0.58) CYP19A1ELANEATML3MBTL1TDP1
SCHEMBL11495143 0.79 CYP19A1 (0.53) CYP19A1ELANEATML3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119529222-A Flexible photosensitive polyurethane film and preparation method thereof 广东工业大学 2025-02-28 CN claimed
CN-114805798-B Heterogeneous catalyst for visible light induced controllable free radical polymerization 福州大学 2023-06-09 CN claimed
CN-114805798-A Heterogeneous catalyst for visible light induced controllable free radical polymerization 福州大学 2022-07-29 CN claimed
WO-2006026053-A1 CATALYTICS ASYMMETRIC ACTIVATION OF UNACTIVATED C-H BONDS, AND COMPOUNDS RELATED THERETO BRANDEIS UNIVERSITY (US) 2006-03-09 WO claimed
JP-8176067-A None JP disclosed
EP-4565586-A1 NOVEL ECTONUCLEOTIDE PYROPHOSPHATASE / PHOSPHODIESTERASE 1 (ENPP-1) INHIBITORS AND USES THEREOF Sravathi Ai Technology Private Limited (IN) 2025-06-11 EP disclosed
CN-119677742-A Novel external nucleotide pyrophosphatase/phosphodiesterase 1 (ENPP 1) inhibitor and application thereof 斯拉瓦蒂人工智能科技私人有限公司 2025-03-21 CN disclosed
CN-119529222-A Flexible photosensitive polyurethane film and preparation method thereof 广东工业大学 2025-02-28 CN disclosed
US-12065541-B2 Thermoplastic resin, optical film made therefrom, diol compound, diester compound MITSUBISHI CHEMICAL CORPORATION (JP) 2024-08-20 US disclosed
CN-113490540-B Fouling-inhibiting ability-imparting agent and water treatment film using same 南洋理工大学 2024-05-31 CN disclosed
WO-2024028727-A1 NOVEL ECTONUCLEOTIDE PYROPHOSPHATASE / PHOSPHODIESTERASE 1 (ENPP-1) INHIBITORS AND USES THEREOF SRAVATHI AI TECHNOLOGY PRIVATE LIMITED (IN) 2024-02-08 WO disclosed
CN-113950500-B Thermoplastic resin, optical film comprising the same, diol compound, and diester compound 三菱化学株式会社 2023-11-03 CN disclosed
US-6362209-B1 ANTIPYRETICS, ANALGESICS, ANTIINFLAMMATORY AGENTS JAPAN TOBACCO INC. (JP) 2002-03-26 US disclosed
US-6306991-B1 TWO PART COATING COMPOSITION WITH TWO CONTAINERS, OXIDATIVE POLYMERS WITH CROSSLINKABLE FUNCTIONAL GROUPS ROHM AND HAAS COMPANY 2001-10-23 US disclosed
US-6149977-A CONTACTING THE OXIDATIVE POLYMER WITH A CATALYTIC AMOUNT OF AN OXIDIZING ENZYME, SUCH AS HORSERADISH PEROXIDASE. ROHM AND HAAS COMPANY (US) 2000-11-21 US disclosed
US-5994381-A ANTIPYRETICS; ANTIINFLAMMATORY AGENTS; ANALGESICS JAPAN TOBACCO, INC. (JP) 1999-11-30 US disclosed
EP-0950669-A2 Method of catalytic crosslinking of polymers and two-pack composition used therein ROHM AND HAAS COMPANY (US) 1999-10-20 EP disclosed
EP-0745596-B1 HETEROAROMATIC OXAZOLE COMPOUNDS AND USE THEREOF JAPAN TOBACCO INC (JP) 1999-05-19 EP disclosed
EP-0745596-A1 HETEROAROMATIC OXAZOLE COMPOUNDS AND USE THEREOF Japan Tobacco Inc. (JP) 1996-12-04 EP disclosed
JP-H08176067-A PRODUCTION OF 4,4'-DIACETOXYBIPHENYL UBE IND LTD 1996-07-09 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12065541-B2 Thermoplastic resin, optical film made therefrom, diol compound, diester compound RTF1, RNF31, RNF10 CYP19A1 675/4885ELANE 2566/4885ATM 3643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.