SCHEMBL5025919

SCHEMBL5025919

O=C(Cl)Oc1cc(OC(=O)Cl)cc(C(=O)O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPMT P51580 3/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
PLA2G2A P14555 1/20 0.43
TTR P02766 1/20 0.41
CA12 O43570 3/20 0.41
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
CA7 P43166 3/20 0.41
CA9 Q16790 3/20 0.41
CA14 Q9ULX7 3/20 0.41
AKR1C3 P42330 1/20 0.39
CA3 P07451 2/20 0.39
CA4 P22748 2/20 0.39
CA6 P23280 2/20 0.39
CA5A P35218 2/20 0.39
CA5B Q9Y2D0 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7753605 0.95 TPMT (0.44) TPMTMEN1KMT2APLA2G2ATTR
SCHEMBL11702300 0.90 TPMT (0.40) TPMTMEN1KMT2APLA2G2ATTR
SCHEMBL11703054 0.88 CA12 (0.56) TPMTMEN1KMT2ATTRCA12
SCHEMBL998315 0.85 KMT2A (0.39) MEN1KMT2ATTRKDM4EALDH1A1
SCHEMBL17237455 0.84 KMT2A (0.37) MEN1KMT2AMAPTHPGDTDP1
SCHEMBL11699992 0.84 MEN1 (0.32) MEN1KMT2AALDH1A1TSHR
SCHEMBL1259679 0.79 AKR1C3 (0.61) KMT2ACA12CA1CA2CA9
SCHEMBL890486 0.79 POLB (0.31) ALDH1A1TSHRPOLB
SCHEMBL417129 0.77 HSD17B10 (0.57) TPMTMEN1KMT2APLA2G2ATTR
SCHEMBL20676026 0.77 MEN1 (0.56) TPMTMEN1KMT2APLA2G2ACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7348113-B2 Electrophotographic photoconductor comprising a polycarbonate resin having a dihydroxy diphenyl ether unit RICOH COMPANY, LTD. (JP) 2008-03-25 US disclosed
US-7071285-B2 Aromatic polycarbonate resin, electrophotographic photoconductor, process cartridge, and electrophotographic image forming method and apparatus RICOH COMPANY, LTD. (JP) 2006-07-04 US disclosed
US-6919419-B2 AROMATIC BLOCK POLYCARBONATE RESIN, DIPHENOL COMPOUND FOR PREPARATION OF THE POLYCARBONATE RESIN, ELECTRO-PHOTOGRAPHIC PHOTOCONDUCTOR, ELECTRO-PHOTOGRAPHIC IMAGE FORMING APPARATUS AND PROCESS, AND PROCESS CARTRIDGE RICOH COMPANY LTD. (JP) 2005-07-19 US disclosed
US-20050106483-A1 Aromatic polycarbonate resin, electrophotographic photoconductor, dihydroxy diphenyl ether compound, and process of manufacturing dihydroxy diphenyl ether compound RICOH COMPANY, LTD. (JP) 2005-05-19 US disclosed
US-20050003287-A1 Aromatic polycarbonate resin, electrophotographic photoconductor, process cartridge, and electrophotographic image forming method and apparatus RICOH COMPANY, LTD. (JP) 2005-01-06 US disclosed
US-6790571-B2 FORMED FROM N-(4-(2,2-BIS(4-HYDROXYPHENYL)VINYL)PHENYL)-N,N BIS(4-TOLYL)AMINE; IMPROVED DURABILITY; FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICE RICOH COMPANY, LTD. (JP) 2004-09-14 US disclosed
US-20040002574-A1 Aromatic block polycarbonate resin, diphenol compound for preparation of the polycarbonate resin, electro-photographic photoconductor, electro-photographic image forming apparatus and process, and process cartridge RICOH COMPANY, LTD. (JP) 2004-01-01 US disclosed
US-6664361-B2 Aromatic polycarbonates; electrography RICOH COMPANY, LTD. (JP) 2003-12-16 US disclosed
US-6576386-B1 AROMATIC BLOCK POLYCARBONATE RESIN, DIPHENOL COMPOUND FOR PREPARATION OF THE POLYCARBONATE RESIN, ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS AND PROCESS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2003-06-10 US disclosed
US-6486293-B1 Electrophotographic photoconductor and method of producing aromatic polycarbonate resin for use in the photoconductor RICOH COMPANY, LTD. (JP) 2002-11-26 US disclosed
EP-0581074-B1 Processes for producing aromatic polycarbonate oligomer and aromatic polycarbonate MITSUI CHEMICALS INC (JP) 1999-03-10 EP disclosed
US-5840454-A Aromatic polycarbonate and electrophotographic photosensitive medium using same RICOH COMPANY, LTD. (JP) 1998-11-24 US disclosed
EP-0600447-B1 Aromatic polycarbonate and production method thereof MITSUI CHEMICALS INC (JP) 1998-10-07 EP disclosed
US-5426170-A Interfacial polymerization of aromatic dihydroxy compound, carbonate precursor, alkali metal or alkaline metal base, water and solvent, endcapping MITSUI TOATSU CHEMICALS, INC. (JP) 1995-06-20 US disclosed
US-5380814-A Molecular weight control MITSUI TOATSU CHEMICALS, INC. (JP) 1995-01-10 US disclosed
US-5359117-A Continuous processing using molecular weight control agent, catalyst, carbonyl halide, solvent and base MITSUI TOATSU CHEMICALS, INC. (JP) 1994-10-25 US disclosed
EP-0600447-A2 Aromatic polycarbonate and production method thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1994-06-08 EP disclosed
EP-0581074-A2 Processes for producing aromatic polycarbonate oligomer and aromatic polycarbonate MITSUI TOATSU CHEMICALS, Inc. (JP) 1994-02-02 EP disclosed
EP-0575870-A1 Aromatic polycarbonate and process for production thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-12-29 EP disclosed
US-4059565-A Process for producing a branched polycarbonate or poly(ester-carbonate) MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1977-11-22 US disclosed