Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22837676 | 0.97 | KMT2A (0.46) | SMN1; SMN2TP53KMT2AMEN1HPGD | |
| SCHEMBL19500900 | 0.97 | KMT2A (0.46) | SMN1; SMN2TP53KMT2AMEN1HPGD | |
| SCHEMBL12591674 | 0.92 | KMT2A (0.41) | SMN1; SMN2TP53KMT2AMEN1HPGD | |
| SCHEMBL23945685 | 0.86 | SMN1; SMN2 (0.44) | SMN1; SMN2TP53KMT2AMEN1HPGD | |
| SCHEMBL16674308 | 0.85 | KMT2A (0.53) | SMN1; SMN2TP53KMT2AMEN1HPGD | |
| SCHEMBL24812855 | 0.85 | KMT2A (0.43) | SMN1; SMN2TP53KMT2AMEN1HPGD | |
| SCHEMBL21107578 | 0.84 | MEN1 (0.44) | SMN1; SMN2KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL22054928 | 0.83 | KMT2A (0.57) | SMN1; SMN2TP53KMT2AMEN1HPGD | |
| SCHEMBL23665082 | 0.83 | KMT2A (0.57) | SMN1; SMN2TP53KMT2AMEN1HPGD | |
| SCHEMBL18908729 | 0.83 | KMT2A (0.57) | SMN1; SMN2TP53KMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | YALE UNIVERSITY | 2020-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | PPP5C, PPP4C, DUSP26 | SMN1; SMN2 1455/4885TP53 153/4885KMT2A 3392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.