Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20372471 | 0.83 | MEN1 (0.34) | MEN1KMT2AEPHX2KDM4EALDH1A1 | |
| SCHEMBL20330475 | 0.83 | GAA (0.32) | MEN1KMT2ATSHR | |
| SCHEMBL20330477 | 0.83 | KDM4E (0.36) | MEN1KMT2AKDM4EALDH1A1CYP2C19 | |
| SCHEMBL21026059 | 0.83 | KDM4E (0.39) | MEN1KMT2AEPHX2KDM4EALDH1A1 | |
| SCHEMBL21341624 | 0.79 | CYP2C19 (0.36) | MEN1KMT2AEPHX2KDM4ECES2 | |
| SCHEMBL20234681 | 0.79 | CES2 (0.34) | MEN1KMT2AEPHX2KDM4ECES2 | |
| SCHEMBL21025933 | 0.78 | MEN1 (0.35) | MEN1KMT2ACES2TSHR | |
| SCHEMBL20325879 | 0.78 | MEN1 (0.35) | MEN1KMT2ACES2TSHR | |
| SCHEMBL20133378 | 0.78 | CES2 (0.37) | EPHX2KDM4EALDH1A1CES2CYP2C19 | |
| SCHEMBL25122859 | 0.78 | KDM4E (0.43) | MEN1KMT2AKDM4EALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | YALE UNIVERSITY | 2020-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | PPP5C, PPP4C, DUSP26 | MEN1 2838/4885KMT2A 3392/4885EPHX2 3787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.