Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 5/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28447321 | 0.85 | STAT3 (0.62) | STAT3ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL28466631 | 0.84 | STAT3 (0.73) | STAT3ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL28445497 | 0.82 | STAT3 (0.64) | STAT3ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL28447880 | 0.80 | STAT3 (0.70) | STAT3ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL28451230 | 0.79 | STAT3 (0.67) | STAT3ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL28451575 | 0.79 | STAT3 (0.64) | STAT3ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL28453179 | 0.79 | STAT3 (0.68) | STAT3ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL28453176 | 0.79 | STAT3 (0.62) | STAT3ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL28445495 | 0.78 | STAT3 (0.62) | STAT3ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL28444266 | 0.77 | STAT3 (0.63) | STAT3ALDH1A1MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | YALE UNIVERSITY | 2020-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | PPP5C, PPP4C, DUSP26 | STAT3 806/4885ALDH1A1 3756/4885MAPT 1352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.