Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28466631 | 0.87 | STAT3 (0.73) | STAT3ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3421633 | 0.85 | ALDH1A1 (0.62) | STAT3ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3921486 | 0.84 | MAPT (0.62) | STAT3ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3423870 | 0.84 | MAPT (0.66) | STAT3ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3419640 | 0.83 | MAPT (0.79) | STAT3ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL13739786 | 0.82 | MEN1 (0.55) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL22374895 | 0.80 | STAT3 (0.80) | STAT3ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL22374686 | 0.79 | STAT3 (0.84) | STAT3ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL14408985 | 0.79 | GCGR (0.58) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL3928773 | 0.78 | ALDH1A1 (0.66) | STAT3ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111763217-B | Thieno-nitrogen heterocyclic compounds, preparation method and application | 上海凌达生物医药有限公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-108191885-B | Piperidinothiophene micromolecule organic compound and application thereof | 华东师范大学 | 2020-08-04 | — | — | CN | disclosed |