Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | DUT | P33316 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GLS | O94925 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25062317 | 0.83 | LMNA (0.42) | ALDH1A1LMNARECQLPOLBMAPT | |
| SCHEMBL16139204 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HPGDSMN1; SMN2DUTLMNA | |
| SCHEMBL9116620 | 0.77 | ALDH1A1 (0.58) | ALDH1A1HPGDSMN1; SMN2DUTLMNA | |
| SCHEMBL21953733 | 0.76 | MEN1 (0.31) | — | |
| SCHEMBL23772645 | 0.75 | ALDH1A1 (0.56) | ALDH1A1HPGDSMN1; SMN2DUTLMNA | |
| SCHEMBL23772642 | 0.75 | ALDH1A1 (0.56) | ALDH1A1HPGDSMN1; SMN2DUTLMNA | |
| SCHEMBL16139220 | 0.72 | ALDH1A1 (0.53) | ALDH1A1HPGDSMN1; SMN2DUTLMNA | |
| SCHEMBL19171550 | 0.72 | SMN1; SMN2 (0.50) | ALDH1A1HPGDSMN1; SMN2DUTLMNA | |
| SCHEMBL19704159 | 0.71 | ALDH1A1 (0.41) | ALDH1A1HPGDSMN1; SMN2DUTRECQL | |
| SCHEMBL9462903 | 0.71 | ALDH1A1 (0.57) | ALDH1A1HPGDSMN1; SMN2DUTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200270218-A1 | SENSORS FOR DETECTION OF NEGATIVELY CHARGED PHOSPHATE-CONTAINING MEMBRANES AND MEMBRANE COMPONENTS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2020-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200270218-A1 | SENSORS FOR DETECTION OF NEGATIVELY CHARGED PHOSPHATE-CONTAINING MEMBRANES AND MEMBRANE COMPONENTS | PHOSPHO1, PTEN, INPPL1 | ALDH1A1 4871/4885HPGD 3832/4885SMN1; SMN2 4797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.