Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.48 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.48 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.43 |
| ▸ | S100A4 | P26447 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10936303 | 0.84 | ALDH1A1 (0.69) | TDP1ALDH1A1S100A4MEN1KMT2A | |
| SCHEMBL2235025 | 0.82 | ALDH1A1 (0.71) | TDP1ALDH1A1PKN1PKN2CDC7 | |
| Hydrochloric Acid SCHEMBL6608463 | 0.81 | ALDH1A1 (0.69) | TDP1ALDH1A1PKN1PKN2CDC7 | |
| SCHEMBL27775375 | 0.80 | TDP1 (0.58) | TDP1ALDH1A1PKN1PKN2CDC7 | |
| SCHEMBL15365347 | 0.80 | TDP1 (0.49) | TDP1ALDH1A1PKN1PKN2CDC7 | |
| SCHEMBL15875693 | 0.79 | ALDH1A1 (0.67) | TDP1ALDH1A1PKN1PKN2CDC7 | |
| SCHEMBL15875692 | 0.79 | ALDH1A1 (0.61) | TDP1ALDH1A1PKN1PKN2CDC7 | |
| SCHEMBL14956543 | 0.79 | TDP1 (0.47) | TDP1ALDH1A1S100A4MEN1KMT2A | |
| SCHEMBL20997818 | 0.78 | MAPT (0.48) | ALDH1A1RAB9AMAPTHTTSMN1; SMN2 | |
| SCHEMBL1460867 | 0.75 | TDP1 (0.61) | TDP1ALDH1A1S100A4KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201599-A1 | CDK Modulators | EXELIXIS, INC. (US) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201599-A1 | CDK Modulators | CDK3, CDK1, CDKL1 | TDP1 706/4885ALDH1A1 2581/4885PKN1 622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.