Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.48 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.48 |
| ▸ | KLK3 | P07288 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5157627 | 0.84 | TDP1 (0.69) | TDP1TSHRSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL2235025 | 0.82 | ALDH1A1 (0.71) | TDP1TSHRSMN1; SMN2ALDH1A1PKN1 | |
| SCHEMBL9550119 | 0.82 | TDP1 (0.78) | TDP1TSHRSMN1; SMN2MAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6608463 | 0.81 | ALDH1A1 (0.69) | TDP1TSHRSMN1; SMN2ALDH1A1PKN1 | |
| SCHEMBL15365347 | 0.80 | TDP1 (0.49) | TDP1SMN1; SMN2ALDH1A1PKN1PKN2 | |
| SCHEMBL2237608 | 0.80 | TDP1 (0.49) | TDP1SMN1; SMN2ALDH1A1PKN1PKN2 | |
| SCHEMBL3538629 | 0.80 | TDP1 (0.58) | TDP1TSHRSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL15875692 | 0.79 | ALDH1A1 (0.61) | TDP1TSHRSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL15875693 | 0.79 | ALDH1A1 (0.67) | TDP1TSHRSMN1; SMN2ALDH1A1PKN1 | |
| SCHEMBL15720127 | 0.77 | TDP1 (0.46) | TDP1TSHRSMN1; SMN2MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679266-A | PIM kinase inhibitors and methods of their use | NOVARTIS AG | 2010-03-24 | — | — | CN | disclosed |