Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA3 | P07451 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL454263 | 0.95 | KDM4E (0.46) | LCKKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL28361770 | 0.93 | KDM4E (0.45) | LCKKDM4EALDH1A1MAPTMEN1 | |
| Methoxymethane SCHEMBL4116870 | 0.92 | KDM4E (0.52) | LCKKDM4EALDH1A1MAPTMEN1 | |
| Sulfuric Acid SCHEMBL28383824 | 0.90 | PAM (0.43) | LCKKDM4EALDH1A1MAPTMEN1 | |
| Methoxymethane SCHEMBL28927442 | 0.90 | KDM4E (0.51) | LCKKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL16191944 | 0.87 | MAOB (0.52) | LCKKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL16191943 | 0.87 | MAOB (0.52) | LCKKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL16290832 | 0.87 | LCK (0.56) | LCKKDM4EALDH1A1MAPTMEN1 | |
| Benzoic Acid SCHEMBL29108683 | 0.84 | TTR (0.49) | KDM4EALDH1A1MAPTMEN1TP53 | |
| Pinosylvin SCHEMBL454262 | 0.83 | LCK (0.71) | LCKKDM4EALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362226-B1 | Diagnostic method for neurodegenerative diseases based on measurement of SIRT1 levels or activity | HARVARD COLLEGE (US) | 2016-02-17 | — | — | EP | disclosed |
| EP-2362226-A1 | Diagnostic method for neurodegenerative diseases based on measurement of SIRT1 levels or activity | The President and Fellows of Harvard College (US) | 2011-08-31 | — | — | EP | disclosed |