SCHEMBL454263

SCHEMBL454263

Oc1cc(O)cc(CC=Cc2ccccc2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.46
ALDH1A1 P00352 5/20 0.46
MAPT P10636 5/20 0.46
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
TP53 P04637 4/20 0.46
CYP3A4 P08684 4/20 0.46
ALOX15 P16050 2/20 0.46
RECQL P46063 1/20 0.46
PAM P19021 1/20 0.46
HPGD P15428 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
HSD17B10 Q99714 3/20 0.43
USP2 O75604 2/20 0.43
TRPV1 Q8NER1 1/20 0.43
PTGER4 P35408 1/20 0.42
PTGER3 P43115 1/20 0.42
PTGER2 P43116 1/20 0.42
LCK P06239 1/20 0.42
SLC5A1 P13866 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28361770 0.98 KDM4E (0.45) KDM4EALDH1A1MAPTMEN1KMT2A
Pinosylvin SCHEMBL2237660 0.95 LCK (0.52) KDM4EALDH1A1MAPTMEN1KMT2A
Methoxymethane SCHEMBL4116870 0.93 KDM4E (0.52) KDM4EALDH1A1MAPTMEN1KMT2A
Methoxymethane SCHEMBL28927442 0.92 KDM4E (0.51) KDM4EALDH1A1MAPTMEN1KMT2A
Sulfuric Acid SCHEMBL28383824 0.92 PAM (0.43) KDM4EALDH1A1MAPTMEN1KMT2A
Benzoic Acid SCHEMBL29108683 0.89 TTR (0.49) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL16191943 0.85 MAOB (0.52) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL16191944 0.85 MAOB (0.52) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL16290832 0.84 LCK (0.56) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL9742983 0.83 MAPT (0.49) KDM4EALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1807 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122031539-A Pine bark polyphenol extract and preparation method and application thereof 北京农学院 2026-05-15 CN claimed
CN-117402197-B Vitex negundo extract and preparation method thereof and identification method of Vitex negundo honey 江苏蜂奥生物科技有限公司 2026-05-15 CN claimed
US-20260130395-A1 Water Dispersible Botanical Compositions AQUILA BLACK LTD (AU) 2026-05-14 US claimed
US-20260078269-A1 POLYMERIC COMPOSITIONS WITH STILBENE-BASED PROCESSING AIDS Cambium Biomaterials, Inc. (US) 2026-03-19 US claimed
EP-4687856-A2 GLP-1R AGONIST AND DPP-4 INHIBITOR COMPOSITIONS AND METHODS OF USING JDS Therapeutics, LLC (US) 2026-02-11 EP claimed
CN-120053406-A Natural product inhibitor for enterococcus faecalis biological film and preparation method and application thereof 海南大学 2025-05-30 CN claimed
CN-120025999-A Mulberry-derived morusin isopentenyl transferase and encoding gene and application thereof 中国科学院杭州医学研究所 2025-05-23 CN claimed
CN-120005740-A Recombinant microorganism for high-level synthesis of polyphenol compounds and application thereof 中国科学院天津工业生物技术研究所 2025-05-16 CN claimed
US-20250144056-A1 ANTIMICROBIAL HOST DEFENSE PEPTIDE-INDUCING COMPOSITIONS AND METHODS OF PRODUCTION AND USE THEREOF BOARD OF REGENTS FOR THE OKLAHOMA AGRICULTURAL AND MECH COLLEGES (US) 2025-05-08 US claimed
CN-119925454-A Application of cajan leaf in rats with chronic myelosuppression caused by MTX 浙江中医药大学 2025-05-06 CN claimed
US-20040199032-A1 Method for isolating phenolic substances or javabiones from wood comprising knotwood HOLMBOM BJARNE (FI) 2004-10-07 US claimed
EP-1395539-A1 A METHOD FOR ISOLATING PHENOLIC SUBSTANCES OR JUVABIONES FROM WOOD COMPRISING KNOTWOOD Holmbom, Bjarne (FI) 2004-03-10 EP claimed
WO-2003026705-A1 METHODS FOR STERILIZING BIOLOGICAL MATERIALS USING FLAVONOID/FLAVONOL STABILIZERS CLEARANT, INC. (US) 2003-04-03 WO claimed
US-20030059338-A1 Methods for sterilizing biological materials using flavonoid/flavonol stabilizers CLEARANT, INC. 2003-03-27 US claimed
WO-2002098830-A1 A METHOD FOR ISOLATING PHENOLIC SUBSTANCES OR JUVABIONES FROM WOOD COMPRISING KNOTWOOD HOLMBOM BJARNE (FI) 2002-12-12 WO claimed
EP-1257636-A2 OZONE AND/OR PATHOGEN-INDUCIBLE GENE EXPRESSION IN PLANTS GSF-Forschungszentrum für Umwelt und Gesundheit GmbH (DE) 2002-11-20 EP claimed
WO-2001059139-A2 OZONE AND/OR PATHOGEN-INDUCIBLE GENE EXPRESSION IN PLANTS GSF-Forschungszentrum für Umwelt und Gesundheit GmbH (DE) 2001-08-16 WO claimed
CN-1270804-A use of diphenyl styrene in cosmetic composition as deodoring active content OREAL (FR) 2000-10-25 CN claimed
EP-0979874-A2 Protein and DNA sequence for pinosylvine-3-O-methyltransferase (PMT) GSF-Forschungszentrum für Umwelt und Gesundheit GmbH (DE) 2000-02-16 EP claimed
CN-1145353-A Epoxy resin, resin composition, and resin-encapsulated semiconductor device SUMITOMO CHEMICAL CO (JP) 1997-03-19 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260130395-A1 Water Dispersible Botanical Compositions TTPA, PNLIP, SRMS KDM4E 4113/4885ALDH1A1 2919/4885MAPT 238/4885
US-20260078269-A1 POLYMERIC COMPOSITIONS WITH STILBENE-BASED PROCESSING AIDS SMCHD1, TERB1, NLRP3 KDM4E 1981/4885ALDH1A1 1739/4885MAPT 337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.