Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL223772 | 1.00 | NPC1 (0.31) | NPC1MAPTRAB9AALDH1A1BCHE | |
| SCHEMBL222571 | 0.95 | ALDH1A1 (0.32) | NPC1MAPTRAB9AALDH1A1BCHE | |
| SCHEMBL222572 | 0.95 | ALDH1A1 (0.32) | NPC1MAPTRAB9AALDH1A1BCHE | |
| SCHEMBL2765970 | 0.93 | NPC1 (0.30) | NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL2763542 | 0.90 | — | — | |
| SCHEMBL221522 | 0.86 | P2RY14 (0.34) | RAB9A | |
| SCHEMBL221521 | 0.86 | P2RY14 (0.34) | RAB9A | |
| SCHEMBL223022 | 0.85 | CYP2C9 (0.33) | NPC1MAPTALDH1A1 | |
| SCHEMBL223021 | 0.85 | CYP2C9 (0.33) | NPC1MAPTALDH1A1 | |
| SCHEMBL2741111 | 0.82 | P2RY14 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431039-B2 | Mesogenic stabilizers | TRANSITIONS OPTICAL, INC. (US) | 2013-04-30 | — | — | US | disclosed |
| US-20120002141-A1 | MESOGENIC STABILIZERS | TRANSITIONS OPTICAL, INC. (US) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120002141-A1 | MESOGENIC STABILIZERS | BMI1, METTL14, PYM1 | NPC1 3019/4885MAPT 1211/4885RAB9A 2145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.