Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21415646 | 0.95 | ALDH1A1 (0.49) | ALDH1A1CYP3A4CA2TSHRMAPK1 | |
| SCHEMBL320723 | 0.89 | ALDH1A1 (0.50) | ALDH1A1CYP3A4CA2TSHRMAPK1 | |
| SCHEMBL15463917 | 0.88 | ALDH1A1 (0.49) | ALDH1A1CYP3A4CA2TSHRMAPK1 | |
| SCHEMBL17112416 | 0.82 | ALDH1A1 (0.48) | ALDH1A1CYP3A4CA2TSHRMAPK1 | |
| SCHEMBL23424467 | 0.82 | ALDH1A1 (0.48) | ALDH1A1CYP3A4CA2TSHRMAPK1 | |
| SCHEMBL13280839 | 0.81 | PRSS1 (0.44) | ALDH1A1CYP3A4CA2TSHRMAPK1 | |
| SCHEMBL29224868 | 0.80 | ALDH1A1 (0.67) | ALDH1A1CYP3A4CA2TSHRMAPK1 | |
| SCHEMBL28937591 | 0.80 | ALDH1A1 (0.59) | ALDH1A1CYP3A4CA2TSHRMAPK1 | |
| SCHEMBL18321151 | 0.79 | ALDH1A1 (0.52) | ALDH1A1CYP3A4CA2TSHRMAPK1 | |
| SCHEMBL322223 | 0.79 | PRSS1 (0.41) | ALDH1A1CYP3A4CA2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536700-B1 | SEMICONDUCTING POLYMERS | MERCK PATENT GMBH (DE) | 2019-10-02 | — | — | EP | disclosed |
| EP-2536700-B1 | SEMICONDUCTING POLYMERS | MERCK PATENT GMBH (DE) | 2019-10-02 | — | — | EP | disclosed |
| US-10155774-B2 | Semiconducting polymers | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2018-12-18 | — | — | US | disclosed |
| US-9365585-B2 | Semiconducting polymers | MERCK PATENT GMBH (DE) | 2016-06-14 | — | — | US | disclosed |
| US-9365585-B2 | Semiconducting polymers | MERCK PATENT GMBH (DE) | 2016-06-14 | — | — | US | disclosed |
| US-9365585-B2 | Semiconducting polymers | MERCK PATENT GMBH (DE) | 2016-06-14 | — | — | US | disclosed |
| US-20150353575-A1 | SEMICONDUCTING POLYMERS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2015-12-10 | — | — | US | disclosed |
| US-20150353575-A1 | SEMICONDUCTING POLYMERS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2015-12-10 | — | — | US | disclosed |
| US-20150353575-A1 | SEMICONDUCTING POLYMERS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2015-12-10 | — | — | US | disclosed |
| EP-2631230-B1 | Semiconducting Polymers | MERCK PATENT GMBH (DE) | 2015-01-21 | — | — | EP | disclosed |
| EP-2631230-B1 | Semiconducting Polymers | MERCK PATENT GMBH (DE) | 2015-01-21 | — | — | EP | disclosed |
| EP-2631230-A1 | Semiconducting Polymers | Merck Patent GmbH (DE) | 2013-08-28 | — | — | EP | disclosed |
| EP-2631230-A1 | Semiconducting Polymers | Merck Patent GmbH (DE) | 2013-08-28 | — | — | EP | disclosed |
| EP-2536700-A2 | SEMICONDUCTING POLYMERS | Merck Patent GmbH (DE) | 2012-12-26 | — | — | EP | disclosed |
| US-20120305853-A1 | SEMICONDUCTING POLYMERS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-12-06 | — | — | US | disclosed |
| US-20120305853-A1 | SEMICONDUCTING POLYMERS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-12-06 | — | — | US | disclosed |
| US-20120305853-A1 | SEMICONDUCTING POLYMERS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-12-06 | — | — | US | disclosed |
| WO-2011098113-A2 | SEMICONDUCTING POLYMERS | MERCK PATENT GMBH (DE) | 2011-08-18 | — | — | WO | disclosed |
| WO-2011098113-A2 | SEMICONDUCTING POLYMERS | MERCK PATENT GMBH (DE) | 2011-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10155774-B2 | Semiconducting polymers | PPOX, OCIAD2, OCIAD1 | ALDH1A1 2581/4885CYP3A4 764/4885CA2 4745/4885 |
| US-20120305853-A1 | SEMICONDUCTING POLYMERS | PPOX, OCIAD2, OCIAD1 | ALDH1A1 2581/4885CYP3A4 764/4885CA2 4745/4885 |
| US-20150353575-A1 | SEMICONDUCTING POLYMERS | PPOX, OCIAD2, OCIAD1 | ALDH1A1 2581/4885CYP3A4 764/4885CA2 4745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.