Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1779961 | 0.90 | L3MBTL1 (0.57) | L3MBTL1BRD4PKMCYP2C19POLB | |
| SCHEMBL1749202 | 0.88 | L3MBTL1 (0.62) | L3MBTL1BRD4PKMCYP2C19POLB | |
| SCHEMBL12347398 | 0.87 | L3MBTL1 (0.55) | L3MBTL1BRD4PKMCYP2C19POLB | |
| SCHEMBL15805310 | 0.87 | L3MBTL1 (0.52) | L3MBTL1PKMCYP2C19POLBALDH3A1 | |
| SCHEMBL12346589 | 0.86 | L3MBTL1 (0.54) | L3MBTL1BRD4PKMCYP2C19POLB | |
| SCHEMBL12354981 | 0.86 | L3MBTL1 (0.54) | L3MBTL1BRD4PKMCYP2C19POLB | |
| SCHEMBL1354366 | 0.86 | L3MBTL1 (0.59) | L3MBTL1BRD4PKMCYP2C19POLB | |
| SCHEMBL28927986 | 0.86 | L3MBTL1 (0.59) | L3MBTL1BRD4PKMCYP2C19POLB | |
| SCHEMBL28735134 | 0.86 | L3MBTL1 (0.59) | L3MBTL1BRD4PKMCYP2C19POLB | |
| SCHEMBL30081932 | 0.86 | L3MBTL1 (0.59) | L3MBTL1BRD4PKMCYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201599-A1 | CDK Modulators | EXELIXIS, INC. (US) | 2011-08-18 | — | — | US | disclosed |
| US-20110201599-A1 | CDK Modulators | EXELIXIS, INC. (US) | 2011-08-18 | — | — | US | disclosed |
| US-20110201599-A1 | CDK Modulators | EXELIXIS, INC. (US) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201599-A1 | CDK Modulators | CDK3, CDK1, CDKL1 | L3MBTL1 1493/4885BRD4 123/4885PKM 689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.