SCHEMBL1354366

SCHEMBL1354366

Cc1ccc(S(=O)(=O)n2ccc3c(Br)ccnc32)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.59
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
PKM P14618 2/20 0.43
CYP2C19 P33261 1/20 0.43
POLB P06746 1/20 0.42
ALDH3A1 P30838 1/20 0.42
HTT P42858 1/20 0.42
NOD1 Q9Y239 1/20 0.42
RAPGEF4 Q8WZA2 2/20 0.41
BRD4 O60885 1/20 0.39
CKS1B P61024 1/20 0.39
SKP2 Q13309 1/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.39
COMT P21964 1/20 0.38
HTR6 P50406 1/20 0.38
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30081932 1.00 L3MBTL1 (0.59) L3MBTL1CA1CA2PKMCYP2C19
SCHEMBL2237896 0.86 L3MBTL1 (0.62) L3MBTL1CA1CA2PKMCYP2C19
SCHEMBL1749202 0.86 L3MBTL1 (0.62) L3MBTL1CA1CA2PKMCYP2C19
SCHEMBL29941031 0.86 CYP2C19 (0.58) L3MBTL1PKMCYP2C19HTTHTR6
SCHEMBL457569 0.86 CYP2C19 (0.58) L3MBTL1PKMCYP2C19HTTHTR6
SCHEMBL28735134 0.83 L3MBTL1 (0.59) L3MBTL1CA1CA2PKMCYP2C19
SCHEMBL29634511 0.83 L3MBTL1 (0.59) L3MBTL1CA1CA2PKMCYP2C19
SCHEMBL28927986 0.83 L3MBTL1 (0.59) L3MBTL1CA1CA2PKMCYP2C19
SCHEMBL1749228 0.83 L3MBTL1 (0.59) L3MBTL1CA1CA2PKMCYP2C19
SCHEMBL1749163 0.83 L3MBTL1 (0.59) L3MBTL1CA1CA2PKMCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115976586-B Forward and reverse pulse electrolytic nickel-tungsten alloy solution, preparation method, electroplating method and nickel-tungsten alloy coating 昆山一鼎工业科技有限公司 2025-03-14 CN claimed
CN-115976586-A Positive and negative pulse electrolytic nickel-tungsten alloy solution, preparation method, electroplating method and nickel-tungsten alloy coating 昆山一鼎工业科技有限公司 2023-04-18 CN claimed
US-20260014147-A1 STAT6 DEGRADERS GILEAD SCIENCES INC (US) 2026-01-15 US disclosed
US-20260001893-A1 SMALL MOLECULE MODULATORS OF STAT6 GILEAD SCIENCES INC (US) 2026-01-01 US disclosed
US-20250340551-A1 SMALL MOLECULE MODULATORS OF STAT6 GILEAD SCIENCES INC (US) 2025-11-06 US disclosed
US-20250325677-A1 STAT6 DEGRADERS GILEAD SCIENCES INC (US) 2025-10-23 US disclosed
US-20250320206-A1 STAT6 DEGRADERS GILEAD SCIENCES INC (US) 2025-10-16 US disclosed
US-20250320205-A1 STAT6 DEGRADERS GILEAD SCIENCES INC (US) 2025-10-16 US disclosed
CN-115976586-B Forward and reverse pulse electrolytic nickel-tungsten alloy solution, preparation method, electroplating method and nickel-tungsten alloy coating 昆山一鼎工业科技有限公司 2025-03-14 CN disclosed
WO-2024110608-A1 PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS NEURALIS (BE) 2024-05-30 WO disclosed
CN-112752757-B Tyrosine amide derivatives as RHO-kinase inhibitors 奇斯药制品公司 2024-01-12 CN disclosed
WO-2008145688-A2 PYRROLOPYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS GLAXO GROUP LIMITED (GB) 2008-12-04 WO disclosed
WO-2008145688-A2 PYRROLOPYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS GLAXO GROUP LIMITED (GB) 2008-12-04 WO disclosed
WO-2008132121-A1 LH-INDAZOLE-3-AMINE COMPOUNDS AS IKK1 INHIBITORS GLAXO GROUP LIMITED (GB) 2008-11-06 WO disclosed
US-20080176891-A1 NOVEL COMPOUNDS GLAXO GROUP LIMITED (GB) 2008-07-24 US disclosed
US-20080146606-A1 NOVEL COMPOUNDS GLAXO GROUP LIMITED (GB) 2008-06-19 US disclosed
WO-2007090141-A2 PYRROLO [2, 3, B] PYRIDINE DERIVATIVES USEFUL AS RAF KINASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2007-08-09 WO disclosed
WO-2007076320-A2 COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 2007-07-05 WO disclosed
US-20070135466-A1 Pyrrolopyridines useful as inhibitors of protein kinase VERTEX PHARMACEUTICALS INCORPORATED 2007-06-14 US disclosed
WO-2003000690-A1 SYNTHESIS OF HETEROCYCLIC COMPOUNDS EMPLOYING MICROWAVE TECHNOLOGY AVENTIS PHARMACEUTICALS INC. (US) 2003-01-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325677-A1 STAT6 DEGRADERS STAT6, STAT5B, STAT1 L3MBTL1 2841/4885CA1 4603/4885CA2 2296/4885
US-20080176891-A1 NOVEL COMPOUNDS NFKBIA, IKBKG, IKBKE L3MBTL1 3702/4885CA1 4572/4885CA2 2716/4885
US-20250340551-A1 SMALL MOLECULE MODULATORS OF STAT6 STAT6, STAT1, STAT5B L3MBTL1 2835/4885CA1 4827/4885CA2 2250/4885
US-20080146606-A1 NOVEL COMPOUNDS NFKBIA, IKBKG, IKBKE L3MBTL1 3702/4885CA1 4572/4885CA2 2716/4885
US-20070135466-A1 Pyrrolopyridines useful as inhibitors of protein kinase JAK2, JAK1, JAK3 L3MBTL1 3383/4885CA1 4478/4885CA2 1774/4885
US-20260001893-A1 SMALL MOLECULE MODULATORS OF STAT6 STAT6, NCOR1, NCOR2 L3MBTL1 2334/4885CA1 2843/4885CA2 873/4885
US-20250320205-A1 STAT6 DEGRADERS STAT6, STAT1, STAT5B L3MBTL1 2778/4885CA1 4613/4885CA2 2130/4885
US-20260014147-A1 STAT6 DEGRADERS STAT6, NCOR1, CBR1 L3MBTL1 3068/4885CA1 2421/4885CA2 561/4885
US-20250320206-A1 STAT6 DEGRADERS STAT6, STAT5B, STAT1 L3MBTL1 2841/4885CA1 4603/4885CA2 2296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.