Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | LATS1 | O95835 | 2/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22380292 | 0.95 | TOP2A (0.38) | TOP2AMEN1KMT2AATMEGFR | |
| SCHEMBL22380484 | 0.87 | MEN1 (0.39) | TOP2AMEN1KMT2AATMNPC1 | |
| SCHEMBL22380482 | 0.87 | MEN1 (0.39) | TOP2AMEN1KMT2AATMNPC1 | |
| SCHEMBL22380174 | 0.87 | GPR3 (0.37) | ATMEGFRADORA1NPC1TP53 | |
| SCHEMBL22380173 | 0.82 | GPR3 (0.37) | ATMEGFRADORA1NPC1TP53 | |
| SCHEMBL22380447 | 0.79 | ACHE (0.34) | TOP2AEGFRADORA1NPC1MAPT | |
| SCHEMBL22380244 | 0.79 | BRD4 (0.35) | EGFRADORA1NPC1MAPTRAB9A | |
| SCHEMBL22380280 | 0.79 | TOP2A (0.38) | TOP2AMEN1KMT2AATMEGFR | |
| SCHEMBL22380287 | 0.79 | TOP2A (0.35) | TOP2AMEN1KMT2AATMEGFR | |
| SCHEMBL22380291 | 0.78 | TOP2A (0.36) | TOP2AMEN1KMT2AATMEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230134398-A1 | Organic Electroluminescent Materials and Devices | UNIVERSAL DISPLAY CORPORATION | 2023-05-04 | — | — | US | disclosed |
| US-20200270262-A1 | Organic Electroluminescent Materials and Devices | UNIVERSAL DISPLAY CORPORATION | 2020-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230134398-A1 | Organic Electroluminescent Materials and Devices | ESRRA, GLRA3, GLRA1 | TOP2A 4127/4885MEN1 2580/4885KMT2A 3835/4885 |
| US-20200270262-A1 | Organic Electroluminescent Materials and Devices | ESRRA, GLRA3, GLRA1 | TOP2A 4127/4885MEN1 2580/4885KMT2A 3835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.