SCHEMBL22380831

SCHEMBL22380831

CC(C)C[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1C[C@@H](O)CN1)C(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)N1CCCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ APLNR P35414 1/20 0.42
▸ NPY2R P49146 7/20 0.41
▸ NPY4R P50391 7/20 0.41
▸ NPY5R Q15761 7/20 0.41
▸ NPY1R P25929 5/20 0.41
▸ GLP1R P43220 6/20 0.40
▸ GIPR P48546 6/20 0.40
▸ OPRM1 P35372 2/20 0.40
▸ OPRD1 P41143 2/20 0.40
▸ OPRK1 P41145 2/20 0.40
▸ RAMP3 O60896 2/20 0.40
▸ CALCR P30988 2/20 0.40
▸ NTSR1 P30989 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22018501 0.98 APLNR (0.44) APLNRNPY2RNPY4RNPY5RNPY1R
SCHEMBL22380750 0.96 APLNR (0.44) APLNROPRM1OPRD1OPRK1RAMP3
SCHEMBL29308339 0.96 NPY2R (0.45) NPY2RNPY4RNPY5RNPY1RGLP1R
SCHEMBL29308380 0.95 APLNR (0.46) APLNROPRM1OPRD1OPRK1RAMP3
SCHEMBL25531202 0.95 APLNR (0.46) APLNROPRM1OPRD1OPRK1RAMP3
SCHEMBL22380832 0.95 NTSR1 (0.45) APLNRNPY2RNPY4RNPY5RNPY1R
SCHEMBL22018307 0.95 APLNR (0.46) APLNROPRM1OPRD1OPRK1RAMP3
SCHEMBL22019133 0.94 RAMP3 (0.44) APLNRNPY2RNPY4RNPY5RNPY1R
SCHEMBL22922816 0.94 APLNR (0.48) APLNRGLP1RGIPROPRM1OPRD1
SCHEMBL22018329 0.94 NPY2R (0.47) APLNRNPY2RNPY4RNPY5RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200270306-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES YUYU PHARMA, INC. (KR) 2020-08-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200270306-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES VIP, IAPP, SCTR APLNR 85/4885NPY2R 337/4885NPY4R 794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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