Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 19/20 | 1.00 |
| ▸ | CA1 | P00915 | 18/20 | 1.00 |
| ▸ | CA12 | O43570 | 18/20 | 1.00 |
| ▸ | CA7 | P43166 | 12/20 | 1.00 |
| ▸ | CA13 | Q8N1Q1 | 12/20 | 1.00 |
| ▸ | CA6 | P23280 | 11/20 | 1.00 |
| ▸ | CA9 | Q16790 | 9/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22380991 | 0.86 | CA12 (1.00) | CA2CA1CA12CA7CA13 | |
| SCHEMBL22380996 | 0.79 | CA1 (1.00) | CA2CA1CA12CA7CA13 | |
| SCHEMBL18424975 | 0.79 | CA1 (1.00) | CA2CA1CA12CA7CA13 | |
| SCHEMBL6201829 | 0.78 | CA12 (0.64) | CA2CA1CA12CA7CA13 | |
| SCHEMBL18805093 | 0.76 | ALPG (0.65) | CA2CA1CA12CA7CA13 | |
| SCHEMBL11572655 | 0.69 | CA2 (0.55) | CA2CA1CA12CA7CA13 | |
| SCHEMBL10830565 | 0.69 | CA2 (0.59) | CA2CA1CA12CA7CA13 | |
| SCHEMBL7857047 | 0.69 | CA2 (0.61) | CA2CA1CA12CA7CA13 | |
| SCHEMBL3642480 | 0.69 | CA2 (0.59) | CA2CA1CA12CA7CA13 | |
| SCHEMBL1327770 | 0.68 | KMT2A (0.61) | CA2CA1CA12CA7CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230149403-A1 | CARBONIC ANHYDRASE ENZYMES FOR REGULATING MAST CELL HEMATOPOIESIS AND TYPE 2 INFLAMMATION | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2023-05-18 | — | — | US | disclosed |
| US-10758537-B2 | Carbonic anhydrase enzymes for regulating mast cell hematopoiesis and type 2 inflammation | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10758537-B2 | Carbonic anhydrase enzymes for regulating mast cell hematopoiesis and type 2 inflammation | CA2, CMA1, CPA3 | CA2 1/4885CA1 10/4885CA12 8/4885 |
| US-20230149403-A1 | CARBONIC ANHYDRASE ENZYMES FOR REGULATING MAST CELL HEMATOPOIESIS AND TYPE 2 INFLAMMATION | CA2, CMA1, CPA3 | CA2 1/4885CA1 10/4885CA12 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.