Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21667376 | 0.91 | KMT2A (0.53) | TP53SMN1; SMN2GPR84MEN1KMT2A | |
| SCHEMBL22383609 | 0.82 | CYP3A4 (0.41) | TP53SMN1; SMN2GPR84MEN1KMT2A | |
| SCHEMBL21667277 | 0.78 | SMN1; SMN2 (0.49) | TP53SMN1; SMN2MEN1KMT2AGLA | |
| SCHEMBL21667365 | 0.76 | SMN1; SMN2 (0.70) | TP53SMN1; SMN2GPR84MEN1KMT2A | |
| SCHEMBL16321957 | 0.73 | CYP3A4 (0.41) | TP53SMN1; SMN2MEN1KMT2AGLA | |
| SCHEMBL22521704 | 0.69 | SMN1; SMN2 (0.76) | TP53SMN1; SMN2GPR84MEN1KMT2A | |
| SCHEMBL16320891 | 0.69 | CYP3A4 (0.74) | TP53SMN1; SMN2MEN1KMT2ACYP3A4 | |
| SCHEMBL21667334 | 0.69 | SMN1; SMN2 (0.60) | TP53SMN1; SMN2GPR84MEN1KMT2A | |
| SCHEMBL16321173 | 0.69 | CYP3A4 (0.74) | TP53SMN1; SMN2MEN1KMT2ACYP3A4 | |
| SCHEMBL16320892 | 0.69 | CYP3A4 (0.74) | TP53SMN1; SMN2MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3702352-A1 | PYRIMIDINEDIONE COMPOUND AGAINST CARDIAC CONDITIONS | Myokardia, Inc. (US) | 2020-09-02 | — | — | EP | disclosed |