Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 8/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19485472 | 1.00 | KLKB1 (0.41) | KLKB1ITGB1ITGA4ITGB3ITGA2B | |
| SCHEMBL16306042 | 0.94 | ITGB1 (0.43) | KLKB1ITGB1ITGA4ITGB3ITGA2B | |
| SCHEMBL17968917 | 0.94 | ITGB1 (0.43) | KLKB1ITGB1ITGA4ITGB3ITGA2B | |
| SCHEMBL16305997 | 0.94 | ITGB1 (0.39) | KLKB1ITGB1ITGA4ITGB3ITGA2B | |
| SCHEMBL16295181 | 0.92 | SUCNR1 (0.41) | KLKB1ITGB1ITGA4ITGB3ITGA2B | |
| SCHEMBL16295180 | 0.92 | SUCNR1 (0.41) | KLKB1ITGB1ITGA4ITGB3ITGA2B | |
| SCHEMBL16375231 | 0.90 | ITGB1 (0.39) | KLKB1ITGB1ITGA4ITGB3ITGA2B | |
| SCHEMBL19485518 | 0.90 | KLKB1 (0.46) | KLKB1ITGB1ITGA4ITGB3ITGA2B | |
| SCHEMBL22384109 | 0.90 | KLKB1 (0.46) | KLKB1ITGB1ITGA4ITGB3ITGA2B | |
| SCHEMBL22384280 | 0.88 | ITGB3 (0.42) | KLKB1ITGB1ITGA4ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008056-B1 | NOVEL GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-12-09 | — | — | EP | disclosed |
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |