Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 5/20 | 0.40 |
| ▸ | MMP3 | P08254 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22384109 | 0.91 | KLKB1 (0.46) | ITGB3ITGA2BITGB1ITGA4BCL2 | |
| SCHEMBL19485518 | 0.91 | KLKB1 (0.46) | ITGB3ITGA2BITGB1ITGA4BCL2 | |
| SCHEMBL22384069 | 0.88 | KLKB1 (0.41) | ITGB3ITGA2BITGB1ITGA4BCL2 | |
| SCHEMBL19485472 | 0.88 | KLKB1 (0.41) | ITGB3ITGA2BITGB1ITGA4BCL2 | |
| SCHEMBL15091950 | 0.86 | ITGB3 (0.54) | ITGB3ITGA2BBCL2 | |
| SCHEMBL15037032 | 0.86 | ITGB3 (0.54) | ITGB3ITGA2BBCL2 | |
| SCHEMBL16305637 | 0.84 | ITGB3 (0.50) | ITGB3ITGA2BBCL2PSMB1PSMB8 | |
| SCHEMBL17968817 | 0.84 | KLKB1 (0.46) | ITGB3ITGA2BITGB1ITGA4KLKB1 | |
| SCHEMBL16306083 | 0.84 | KLKB1 (0.46) | ITGB3ITGA2BITGB1ITGA4KLKB1 | |
| SCHEMBL17995088 | 0.83 | KLKB1 (0.43) | ITGB3ITGA2BITGB1ITGA4KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |