Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22756136 | 0.91 | ITGB1 (0.42) | ITGB3ITGA2BITGB1ITGA4 | |
| SCHEMBL22448943 | 0.90 | RARB (0.39) | RARBITGB3ITGA2BPPARGPPARA | |
| SCHEMBL15020017 | 0.88 | ITGB3 (0.51) | RARBITGB3ITGA2BPPARGPPARA | |
| SCHEMBL22384107 | 0.88 | RARB (0.39) | RARBITGB3ITGA2BPPARGPPARA | |
| SCHEMBL20426311 | 0.88 | ITGB1 (0.43) | RARBITGB3ITGA2BPPARGPPARA | |
| SCHEMBL22449298 | 0.88 | ITGB3 (0.51) | RARBITGB3ITGA2BPPARGPPARA | |
| SCHEMBL22449285 | 0.88 | ITGB3 (0.51) | RARBITGB3ITGA2BPPARGPPARA | |
| SCHEMBL22449249 | 0.88 | ITGB3 (0.51) | RARBITGB3ITGA2BPPARGPPARA | |
| SCHEMBL15037035 | 0.88 | ITGB3 (0.51) | RARBITGB3ITGA2BPPARGPPARA | |
| SCHEMBL15096631 | 0.88 | ITGB3 (0.51) | RARBITGB3ITGA2BPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791112-B1 | CARBOXYLIC ACID DERIVATIVES COMPRISING FOUR CYCLES ACTING AS GLP-1 RECEPTOR MODULATORS FOR THERAPY OF DISEASES SUCH AS DIABETES | CELGENE INT II SÀRL (CH) | 2020-09-23 | — | — | EP | disclosed |
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |