Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 11/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.40 |
| ▸ | PLG | P00747 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KLK1 | P06870 | 3/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16306073 | 0.92 | ITGB1 (0.50) | ITGB1ITGA4KLKB1ITGB3ITGA2B | |
| SCHEMBL16305708 | 0.92 | ITGB1 (0.50) | ITGB1ITGA4KLKB1ITGB3ITGA2B | |
| SCHEMBL22384144 | 0.92 | ITGB1 (0.50) | ITGB1ITGA4KLKB1ITGB3ITGA2B | |
| SCHEMBL16305712 | 0.92 | ITGB1 (0.50) | ITGB1ITGA4KLKB1ITGB3ITGA2B | |
| SCHEMBL16305934 | 0.92 | ITGB1 (0.50) | ITGB1ITGA4KLKB1ITGB3ITGA2B | |
| SCHEMBL22384071 | 0.91 | RARB (0.39) | ITGB1ITGA4ITGB3ITGA2B | |
| SCHEMBL22756145 | 0.89 | ITGB1 (0.40) | ITGB1ITGA4KLKB1ITGB3ITGA2B | |
| SCHEMBL15037158 | 0.89 | ITGB1 (0.42) | ITGB1ITGA4KLKB1ITGB3ITGA2B | |
| SCHEMBL15037227 | 0.88 | ITGB1 (0.43) | ITGB1ITGA4KLKB1ITGB3ITGA2B | |
| SCHEMBL16306003 | 0.88 | ITGB1 (0.43) | ITGB1ITGA4KLKB1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008056-B1 | NOVEL GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-12-09 | — | — | EP | disclosed |