Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | TACR3 | P29371 | 5/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TACR2 | P21452 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25366914 | 0.88 | TACR3 (0.59) | TACR3ROCK2MEN1KMT2ABCL2L1 | |
| SCHEMBL16295648 | 0.86 | NR1H4 (0.50) | NR1H4MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL28830857 | 0.80 | HPGDS (0.68) | NR1H4RAB9ANPC1LMNAL3MBTL1 | |
| SCHEMBL12443254 | 0.79 | NR1H4 (0.80) | NR1H4ROCK2MEN1KMT2ANPC1 | |
| SCHEMBL16306136 | 0.78 | HIF1A (0.45) | NR1H4ROCK2CA1CA2RORC | |
| SCHEMBL12862989 | 0.77 | KMT2A (0.53) | TACR3MEN1KMT2ALMNATACR2 | |
| SCHEMBL4464301 | 0.77 | NR1H4 (0.55) | NR1H4MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL24510641 | 0.77 | RAB9A (0.70) | MEN1KMT2ARAB9ANPC1POLB | |
| SCHEMBL7446914 | 0.77 | TACR3 (0.44) | TACR3ROCK2MEN1KMT2ABCL2L1 | |
| SCHEMBL30530198 | 0.76 | HPGDS (0.61) | NR1H4RAB9ALMNAALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |