Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.39 |
| ▸ | LHCGR | P22888 | 1/20 | 0.39 |
| ▸ | CBX4 | O00257 | 2/20 | 0.39 |
| ▸ | CBX7 | O95931 | 2/20 | 0.39 |
| ▸ | CDYL2 | Q8N8U2 | 2/20 | 0.39 |
| ▸ | CBX8 | Q9HC52 | 2/20 | 0.39 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16306015 | 1.00 | TDP1 (0.42) | TDP1CTSSCTSKL3MBTL1CTSL | |
| SCHEMBL22756194 | 0.90 | TDP1 (0.43) | TDP1CTSSCTSKL3MBTL1CTSL | |
| SCHEMBL16305640 | 0.90 | TDP1 (0.43) | TDP1CTSSCTSKL3MBTL1CTSL | |
| SCHEMBL28534838 | 0.90 | TDP1 (0.43) | TDP1CTSSCTSKL3MBTL1CTSL | |
| SCHEMBL16343523 | 0.89 | L3MBTL1 (0.45) | CTSSCTSKL3MBTL1CTSLCTSB | |
| SCHEMBL22384187 | 0.87 | LY96 (0.43) | TDP1CTSSCTSKL3MBTL1LY96 | |
| SCHEMBL16294807 | 0.87 | PPARG (0.45) | L3MBTL1CBX4CBX7CDYL2CBX8 | |
| SCHEMBL16295907 | 0.87 | PPARG (0.45) | L3MBTL1CBX4CBX7CDYL2CBX8 | |
| SCHEMBL16295908 | 0.87 | PPARG (0.45) | L3MBTL1CBX4CBX7CDYL2CBX8 | |
| SCHEMBL22756207 | 0.86 | TDP1 (0.39) | TDP1CTSSCTSKL3MBTL1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008056-B1 | NOVEL GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-12-09 | — | — | EP | disclosed |
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |