Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CBX4 | O00257 | 2/20 | 0.40 |
| ▸ | CBX7 | O95931 | 2/20 | 0.40 |
| ▸ | CDYL2 | Q8N8U2 | 2/20 | 0.40 |
| ▸ | CBX8 | Q9HC52 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 7/20 | 0.39 |
| ▸ | CTSK | P43235 | 5/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 3/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16305640 | 1.00 | TDP1 (0.43) | TDP1CTSBL3MBTL1CBX4CBX7 | |
| SCHEMBL28534838 | 1.00 | TDP1 (0.43) | TDP1CTSBL3MBTL1CBX4CBX7 | |
| SCHEMBL16342898 | 0.91 | MAPT (0.46) | TDP1ROCK2MAPTPOLBRECQL | |
| SCHEMBL15037039 | 0.91 | MAPT (0.46) | TDP1ROCK2MAPTPOLBRECQL | |
| SCHEMBL16306015 | 0.90 | TDP1 (0.42) | TDP1CTSBL3MBTL1CBX4CBX7 | |
| SCHEMBL22384129 | 0.90 | TDP1 (0.42) | TDP1CTSBL3MBTL1CBX4CBX7 | |
| SCHEMBL16294791 | 0.89 | CTSB (0.45) | CTSBL3MBTL1CBX4CBX7CDYL2 | |
| SCHEMBL22384060 | 0.86 | L3MBTL1 (0.45) | TDP1CTSBL3MBTL1CTSSCTSK | |
| SCHEMBL22167206 | 0.86 | TDP1 (0.41) | TDP1CTSBL3MBTL1CTSSCTSK | |
| SCHEMBL16305782 | 0.86 | TDP1 (0.41) | TDP1CTSBL3MBTL1CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008056-B1 | NOVEL GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-12-09 | — | — | EP | disclosed |