Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT6 | P42226 | 6/20 | 0.39 |
| ▸ | STAT5A | P42229 | 5/20 | 0.39 |
| ▸ | STAT5B | P51692 | 5/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 5/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15037156 | 0.91 | L3MBTL1 (0.44) | PRCPACEACE2L3MBTL1ITGB1 | |
| SCHEMBL19465510 | 0.91 | L3MBTL1 (0.44) | PRCPACEACE2L3MBTL1ITGB1 | |
| SCHEMBL16342948 | 0.91 | L3MBTL1 (0.44) | PRCPACEACE2L3MBTL1ITGB1 | |
| SCHEMBL16295171 | 0.91 | L3MBTL1 (0.44) | PRCPACEACE2L3MBTL1ITGB1 | |
| SCHEMBL15037148 | 0.91 | L3MBTL1 (0.44) | PRCPACEACE2L3MBTL1ITGB1 | |
| SCHEMBL16305670 | 0.90 | CMA1 (0.39) | PRCPACEITGB3ITGA2BACE2 | |
| SCHEMBL16380213 | 0.89 | L3MBTL1 (0.42) | PRCPACEACE2L3MBTL1ITGB1 | |
| SCHEMBL16305656 | 0.89 | PRCP (0.39) | PRCPACEITGB3ITGA2BACE2 | |
| SCHEMBL16295350 | 0.88 | ACE (0.46) | PRCPACEITGB3ITGA2BACE2 | |
| SCHEMBL16343395 | 0.88 | ACE (0.46) | PRCPACEITGB3ITGA2BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |