Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 13/20 | 0.48 |
| ▸ | ADCY6 | O43306 | 5/20 | 0.44 |
| ▸ | ADCY3 | O60266 | 5/20 | 0.44 |
| ▸ | ADCY9 | O60503 | 5/20 | 0.44 |
| ▸ | ADCY5 | O95622 | 5/20 | 0.44 |
| ▸ | ADCY8 | P40145 | 5/20 | 0.44 |
| ▸ | ADCY7 | P51828 | 5/20 | 0.44 |
| ▸ | ADCY2 | Q08462 | 5/20 | 0.44 |
| ▸ | ADCY1 | Q08828 | 5/20 | 0.44 |
| ▸ | ADCY4 | Q8NFM4 | 5/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16306009 | 0.90 | GCGR (0.47) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL16306096 | 0.87 | SRC (0.45) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL16305696 | 0.87 | SRC (0.45) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL16306008 | 0.87 | SRC (0.45) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL16306007 | 0.86 | L3MBTL1 (0.45) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL16306225 | 0.84 | L3MBTL1 (0.46) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL16305376 | 0.80 | GCGR (0.52) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL16305379 | 0.80 | GCGR (0.52) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL16305835 | 0.80 | GCGR (0.52) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL16306221 | 0.79 | GCGR (0.53) | GCGRADCY6ADCY3ADCY9ADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |