Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.56 |
| ▸ | GCGR | P47871 | 4/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.43 |
| ▸ | PPARG | P37231 | 8/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.40 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.40 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.40 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.40 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15037199 | 0.85 | NR1H4 (0.53) | NR1H4GCGRPPARGPPARAPPARD | |
| SCHEMBL22449283 | 0.85 | NR1H4 (0.53) | NR1H4GCGRPPARGPPARAPPARD | |
| SCHEMBL22449213 | 0.85 | NR1H4 (0.53) | NR1H4GCGRPPARGPPARAPPARD | |
| SCHEMBL15037127 | 0.85 | NR1H4 (0.53) | NR1H4GCGRPPARGPPARAPPARD | |
| SCHEMBL22384052 | 0.84 | PPARG (0.45) | NR1H4GCGREPHX2PPARGPPARA | |
| SCHEMBL16305823 | 0.80 | GCGR (0.51) | NR1H4GCGREGLN1L3MBTL1ADCY6 | |
| SCHEMBL16305970 | 0.76 | PLG (0.47) | GCGRPPARGPPARAPPARDL3MBTL1 | |
| SCHEMBL15037187 | 0.76 | CA2 (0.57) | NR1H4EPHX2MEN1NPC1RAB9A | |
| SCHEMBL22449044 | 0.76 | CA2 (0.57) | NR1H4EPHX2MEN1NPC1RAB9A | |
| SCHEMBL22449235 | 0.76 | CA2 (0.57) | NR1H4EPHX2MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |