Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 13/20 | 0.38 |
| ▸ | CCR1 | P32246 | 4/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP10 | P09238 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834664 | 0.92 | CCR1 (0.38) | CCR1ACE2 | |
| SCHEMBL20427367 | 0.86 | CCR1 (0.41) | CCR1 | |
| SCHEMBL17834627 | 0.85 | CCR1 (0.42) | CCR1 | |
| SCHEMBL17834462 | 0.83 | CCR1 (0.41) | CCR1 | |
| SCHEMBL17834859 | 0.82 | CCR1 (0.40) | DGAT1CCR1 | |
| SCHEMBL17834490 | 0.82 | CCR1 (0.40) | CCR1 | |
| SCHEMBL17834864 | 0.82 | CCR1 (0.41) | CCR1 | |
| SCHEMBL17834437 | 0.81 | CCR1 (0.41) | CCR1 | |
| SCHEMBL17834671 | 0.81 | CCR1 (0.39) | DGAT1CCR1 | |
| SCHEMBL17532293 | 0.80 | ALDH1A1 (0.36) | CCR1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |