Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | MGAM | O43451 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17309314 | 0.86 | ALDH1A1 (0.61) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL17302233 | 0.75 | CA9 (0.68) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL17302215 | 0.74 | CFTR (0.51) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL17302214 | 0.74 | CA9 (0.50) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL19096222 | 0.73 | FAAH (0.67) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL19481512 | 0.73 | CA9 (0.76) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL17309309 | 0.73 | CA9 (0.76) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL12912674 | 0.71 | S1PR3 (0.62) | FAAH | |
| SCHEMBL12912678 | 0.71 | S1PR1 (0.62) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12912685 | 0.70 | S1PR1 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3148541-B1 | THIAZOLIDINONES AS CELLULAR ANANDAMIDE UPTAKE INHIBITORS AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS AND INFLAMMATION, IN PARTICULAR NEUROINFLAMMATION | UNIV BERN (CH) | 2020-09-02 | — | — | EP | disclosed |