Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 10/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.49 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cholate SCHEMBL18485247 | 0.89 | GPBAR1 (0.64) | GPBAR1CYP3A4NR1H4PDE3ATDP1 | |
| Cholate SCHEMBL18472024 | 0.89 | GPBAR1 (0.64) | GPBAR1CYP3A4NR1H4PDE3ATDP1 | |
| Cholate SCHEMBL19268301 | 0.89 | GPBAR1 (0.64) | GPBAR1CYP3A4NR1H4PDE3ATDP1 | |
| Cholate SCHEMBL19273280 | 0.89 | GPBAR1 (0.64) | GPBAR1CYP3A4NR1H4PDE3ATDP1 | |
| Cholate SCHEMBL12568048 | 0.89 | GPBAR1 (0.64) | GPBAR1CYP3A4NR1H4PDE3ATDP1 | |
| Cholate SCHEMBL29568257 | 0.87 | ALDH1A1 (0.66) | GPBAR1CYP3A4NR1H4PDE3AUSP2 | |
| SCHEMBL21533367 | 0.80 | GPBAR1 (0.81) | GPBAR1CYP3A4NR1H4PDE3AUSP2 | |
| SCHEMBL20409459 | 0.80 | GPBAR1 (0.81) | GPBAR1CYP3A4NR1H4PDE3AUSP2 | |
| SCHEMBL409697 | 0.80 | GPBAR1 (0.81) | GPBAR1CYP3A4NR1H4PDE3AUSP2 | |
| SCHEMBL12251424 | 0.80 | GPBAR1 (0.81) | GPBAR1CYP3A4NR1H4PDE3AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200277598-A1 | Peptide Oligonucleotide Conjugates | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2020-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200277598-A1 | Peptide Oligonucleotide Conjugates | SNRPE, SMN1; SMN2, UPF1 | GPBAR1 1805/4885CYP3A4 4811/4885NR1H4 781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.