SCHEMBL22389237

SCHEMBL22389237

CC1(C)c2cc(N(c3ccc(-c4ccccc4)cc3)c3ccc4c(c3)C(C)(C)c3cc5c(cc3-4)C(C)(C)c3ccc4oc6ccccc6c4c3-5)ccc2-c2cc3c(cc21)-c1c(ccc2oc4ccccc4c12)C3(C)C

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALK Q9UM73 5/20 0.32
WEE1 P30291 1/20 0.32
PLA2G2A P14555 1/20 0.31
PLA2G4A P47712 1/20 0.31
TNKS O95271 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20023314 0.95 ALK (0.33) ALKWEE1PLA2G2APLA2G4ATNKS
SCHEMBL22388853 0.95 ALK (0.33) ALKMAPT
SCHEMBL22388859 0.94 ALK (0.32) ALKWEE1PLA2G2APLA2G4A
SCHEMBL20927715 0.94 ALK (0.32) ALKWEE1
SCHEMBL23743415 0.94 ALK (0.33) ALKWEE1PLA2G2APLA2G4ATNKS
SCHEMBL22389063 0.94 ALK (0.35) ALKMAPT
SCHEMBL22389139 0.93 PGR (0.34)
SCHEMBL21790634 0.93 CDC14B (0.31) WEE1
SCHEMBL23743420 0.93 ALK (0.31) ALKWEE1
SCHEMBL23743461 0.93 ALK (0.32) ALKWEE1PLA2G2APLA2G4ATNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230225195-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PERFORMANCE MATERIALS GERMANY GMBH (DE) 2023-07-13 US disclosed
US-20230225195-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PERFORMANCE MATERIALS GERMANY GMBH (DE) 2023-07-13 US disclosed
US-11578063-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-02-14 US disclosed
US-20200277284-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200277284-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, EFNA1, EPCAM ALK 2858/4885WEE1 2185/4885PLA2G2A 3967/4885
US-11578063-B2 Materials for organic electroluminescent devices GPX1, EPCAM, EFNA1 ALK 2189/4885WEE1 1950/4885PLA2G2A 3945/4885
US-20230225195-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES H1-0, H1-2, H1-4 ALK 1406/4885WEE1 1333/4885PLA2G2A 2798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.