SCHEMBL2239337

SCHEMBL2239337

CCC(c1ccccc1)[Si]1(C)CCCCO1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
TDP1 Q9NUW8 1/20 0.32
TRPA1 O75762 1/20 0.32
AOC3 Q16853 1/20 0.32
TAAR1 Q96RJ0 2/20 0.31
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10936708 0.79 CYP2D6 (0.32) AOC3ALDH1A1L3MBTL1
SCHEMBL17048844 0.72 SIGMAR1 (0.38) TRPA1TAAR1
SCHEMBL2404033 0.72 TAAR1 (0.39) TRPA1AOC3TAAR1ALDH1A1L3MBTL1
SCHEMBL9237606 0.71 TAAR1 (0.33) TRPA1TAAR1TSHR
SCHEMBL7771377 0.70 TAAR1 (0.39) TRPA1AOC3TAAR1ALDH1A1L3MBTL1
SCHEMBL1463127 0.67
SCHEMBL2703050 0.67
SCHEMBL28347105 0.67
SCHEMBL3210180 0.67
SCHEMBL8163815 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106232791-A Cleaning compositions comprising alkoxylated polyalkyleneimines, organomodified silicones and silicone-based diluents 宝洁公司 2016-12-14 CN disclosed
US-20110190467-A1 Biological Polysiloxanes VISION CRC LIMITED (AU) 2011-08-04 US disclosed
US-20090276042-A1 Biological Polysiloxanes VISION CRC LIMITED (AU) 2009-11-05 US disclosed
EP-2021399-A1 BIOLOGICAL POLYSILOXANES VISION CRC LIMITED (AU) 2009-02-11 EP disclosed
WO-2007128051-A1 BIOLOGICAL POLYSILOXANES VISION CRC LIMITED (AU) 2007-11-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090276042-A1 Biological Polysiloxanes PBK, B2M, CD79B LMNA 390/4885TDP1 4683/4885TRPA1 2996/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.