Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17048844 | 0.83 | SIGMAR1 (0.38) | TAAR1SIGMAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL10936708 | 0.71 | CYP2D6 (0.32) | SLC6A3CYP2D6 | |
| SCHEMBL2239337 | 0.71 | LMNA (0.34) | TAAR1TRPA1TSHR | |
| SCHEMBL9308520 | 0.69 | TP53 (0.31) | — | |
| SCHEMBL16459396 | 0.69 | — | — | |
| SCHEMBL16461174 | 0.68 | TRPA1 (0.33) | TRPA1 | |
| SCHEMBL16460379 | 0.68 | — | — | |
| SCHEMBL338865 | 0.67 | SLC6A3 (0.33) | TAAR1SIGMAR1SLC6A3CYP2A6SLC18A2 | |
| SCHEMBL16459657 | 0.67 | — | — | |
| SCHEMBL4355743 | 0.65 | CALM1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0667029-A1 | THIXOTROPIC MAGNETORHEOLOGICAL MATERIALS | LORD CORPORATION (US) | 1995-08-16 | — | — | EP | claimed |
| EP-0667029-A4 | THIXOTROPIC MAGNETORHEOLOGICAL MATERIALS. | LORD CORP (US) | 1995-06-13 | — | — | EP | claimed |
| WO-1994010693-A1 | THIXOTROPIC MAGNETORHEOLOGICAL MATERIALS | LORD CORPORATION (US) | 1994-05-11 | — | — | WO | claimed |