Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 15/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22395389 | 0.91 | POLB (0.55) | ATF4POLBLMNAGALR3STAT3 | |
| SCHEMBL30682426 | 0.91 | POLB (0.55) | ATF4POLBLMNAGALR3STAT3 | |
| SCHEMBL22395370 | 0.90 | ATF4 (0.60) | ATF4 | |
| SCHEMBL22395375 | 0.90 | ATF4 (0.60) | ATF4 | |
| SCHEMBL30682488 | 0.89 | ATF4 (0.55) | ATF4GALR3 | |
| SCHEMBL22395349 | 0.89 | ATF4 (0.55) | ATF4GALR3 | |
| SCHEMBL21117011 | 0.87 | ATF4 (0.56) | ATF4POLBLMNAMAPK1 | |
| SCHEMBL19577378 | 0.86 | ATF4 (0.55) | ATF4POLB | |
| SCHEMBL30445912 | 0.86 | ATF4 (0.55) | ATF4POLB | |
| SCHEMBL22395368 | 0.85 | ATF4 (0.56) | ATF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112204006-B | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2023-11-28 | — | — | CN | disclosed |
| EP-3704089-A1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | Calico Life Sciences LLC (US) | 2020-09-09 | — | — | EP | disclosed |